Epidemiological modelling to deliver better care for Australian patients with myeloma (EpiMap Myeloma)

Funding Agency

Australian Government Medical Research Future Fund (MRFF) Preventive and Public Health - Targeted Health System and Community Organisation Research Grant

Project period

2020-2023

Investigators/CHE Researchers

Dennis Petrie, Anthony Harris, Laura Fanning, Adam Irving

Left to right: Adam Irving, Anthony Harris, Laura Fanning, Dennis Petrie

Project Description

This is a collaborative project with A/Professor Zoe McQuilten, Professor Erica Wood and Professor Andrew Spencer from the School of Public Health and Preventive Medicine.
Our project will develop and validate a novel patient-level simulation model to estimate patients in Australia with multiple myeloma (MM) who will require treatment over the next five years, and their associated quality of life and costs. The model will use real world data from the Myeloma and Related Diseases Registry linked to Commonwealth administrative data, be validated with international evidence, and utilise unique modelling applicable to MM disease trajectories and outcomes. The project will address a critical knowledge gap in MM, as the current prevalence and future incidence of MM in Australia is unknown, the treatment pathway for MM is highly complex and there is a host of emerging therapeutics which will continue to escalate treatment complexity and costs, and clinical trials are rarely generalisable to the broader MM population. The model will be available for use in Commonwealth decision making for future funding of high-cost therapies for MM.