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Dominika and Hans Elmlund Laboratory

Structure and Dynamics of Macromolecules by Cryo-EM

Welcome to the Dominika and Hans Elmlund Lab

Jointly co-led by Dr Dominika Elmlund and Dr Hans Elmlund, our lab uses cryogenic electron microscopy (cryo-EM) to elucidate the structure and dynamics of large macromolecules involved in processes of fundamental biological and medical importance.

We're both part of the Monash Biomedicine Discovery Institute, and members of the Cancer and Infection & Immunity Programs, and the Department of Biochemistry and Molecular Biology. Dr Hans Elmlund is also a member of the Development & Stem Cells Program.

Dr Dominika Elmlund

My global research connections, partners and funding can be viewed on my Monash Research Profile.

If you are a student interested in doing research in our lab, visit Supervisor Connect.

Click the links below to connect with me on Twitter, ORCID, Google Scholar and LinkedIn.

Dr Hans Elmlund

My global research connections, partners and funding can be viewed on my Monash Research Profile.

If you are a student interested in doing research in our lab, visit Supervisor Connect.

Click the links below to connect with me on ORCID and Google Scholar.

For access to software, tutorials and manuals on cryo-EM image processing, visit our SIMPLE
(Single-particle IMage Processing Linux Engine) website.

Our research

In addition to understanding the structure and dynamics of large macromolecules of medical importance, we also develop new computational methods for solving the most challenging problems in cryo-EM image processing and integrative structural biology. Biological topics include cancer biology, transcription regulation & mRNA export. Cryo-EM images will be acquired at the Clive & Vera Ramaciotti Centre for Structural Cryo-EM, housing the world-class FEI Titan KRIOS instrument.

  • Methods for single-particle analysis
  • Transcriptional control in Eukaryotes
  • Housekeeping transcriptional control: the TFIID master regulator
  • Stress-inducible transcriptional control: the SAGA master regulator

Lab members

We are committed to excellence in research.

Publications

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News

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Join Our Lab

We're always interested in collaborating with bright and motivated researchers, clinicians and industry. Whether you want to research, study or partner with us to accelerate our discoveries, find out about the work we do.

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