Skip to Content

Hobbs Laboratory

Germline Stem Cells

Welcome to the Hobbs Lab

The main focus of the laboratory is to define molecular mechanisms underlying adult stem cell function through use of germline stem cells from the mouse testis as a model system.

We're part of the Monash Biomedicine Discovery Institute, and a member of the Development & Stem Cells Program and the Department of Anatomy and Developmental Biology and we’re also part of the Australian Regenerative Medicine Institute.

Dr Robin Hobbs

My global research connections, partners and funding can be viewed on my Monash Research Profile.

If you are a student interested in doing research in our lab, visit Supervisor Connect.

Click the links below to connect with me on Twitter, ORCID, Google Scholar and LinkedIn.

Our research

In adult testis, there is a population of germline stem cells (known as spermatogonial stem cells or SSCs) needed for life-long production of spermatozoa and fertility. SSC maintenance is dependent on crosstalk between cell-intrinsic regulators and growth factors produced from a stem cell niche. We have characterised key transcription factors and growth factor signalling pathways involved in self-renewal and differentiation of SSCs. Through use of mouse models, we aim to define cellular pathways regulating SSC function.

Lab members

We are committed to excellence in research.

Publications

View our chosen highlighted key publications.

Read more

News

We want to share our research discoveries & successes with you.

Read more

Join Our Lab

We're always interested in collaborating with bright and motivated researchers, clinicians and industry. Whether you want to research, study or partner with us to accelerate our discoveries, find out about the work we do.

Find out more