Monash discoveries point to new breast cancer treatment

Dr Antonella Papa

MedicalXpress, BrightSurf and the Knowridge Science Report all ran stories on the findings of a study by BDI researchers that suggested a new combination of treatments that may help breast cancer patients with certain gene mutations. The study, published in Molecular Cell and led by Dr Antonella Papa, identified potential new treatments for patients who lacked PTEN, a gene that suppresses tumours, and/or have mutations in the cancer gene PI3K. Mutations in either PTEN or PI3K alone occur in almost 50 per cent of breast cancer patients. In addition, 10 per cent of breast cancer patients have combined genetic alterations in these two genes. “These patients could benefit from our findings,” Dr Papa said.