Partha Das Laboratory
Gene Regulation
Welcome to the Partha Das Lab
Our laboratory focuses on how epigenetic (DNA and histone modifications) and epi-transcriptomic (RNA modifications) changes control gene expression programs in embryonic stem cells (ESCs), neural stem cells and differentiated cells under normal and pathological conditions, such as cancers and neurodevelopmental disorders.
We're part of the Monash Biomedicine Discovery Institute, and a member of the Development & Stem Cells Program, and the Department of Anatomy and Developmental Biology.
Dr Partha Das
My global research connections, partners and funding can be viewed on my Monash Research Profile.
Click the links below to connect with me on ORCID, Google Scholar and LinkedIn.
Our research
We use various experimental approaches and cutting-edge technologies including – cell and molecular biology, biochemistry, CRISPRs, CRISPR screens (using sgRNAs to target all the genes in the genome, epigenetic regulators and regulatory elements), NGS (ChIP-seq, ATAC-seq, Hi-C, RNA-seq, m6A RNA-seq, m5C RNA-seq, Ribo-seq, PRO-seq), proteomics, bioinformatics, computational biology to understand the gene regulation under physiological conditions and diseases.
- Epigenetics
- Epitranscriptomics
- Embryonic stem cells and cortical organoids
- Neurodevelopmental disorders
Lab members
We are committed to excellence in research.
Join Our Lab
We're always interested in collaborating with bright and motivated researchers, clinicians and industry. Whether you want to research, study or partner with us to accelerate our discoveries, find out about the work we do.