Recent research publications

2013

  • Zhao, Z., Liu, J., Hahn, M., Qiao, S., Middelberg, A.P., He, L., 2013, Encapsulation of lipase in mesoporous silica yolk-shell spheres with enhanced enzyme stability, RSC Advances: An International Journal to Further the Chemical Sciences [E], vol Early View, R S C Publications, UK, pp. 1-8.
  • Zhao, Z., Tian, J., Wu, Z., Liu, J., Zhao, D., Shen, W., He, L., 2013, Enhancing enzymatic stability of bioactive papers by implanting enzyme-immobilized mesoporous silica nanorods into paper, Journal of Materials Chemistry B [P], vol 1, issue 37, R S C Publications, UK, pp. 4719-4722.
  • Dimitrijev-Dwyer, M., He, L., James, M., Nelson, A., Middelberg, A.P., 2013, Insights into the role of protein molecule size and structure on interfacial properties using designed sequences, Journal Of The Royal Society Interface [P], vol 10, The Royal Society Publishing, UK, pp. 1-12.

2012

  • Chen, X., Wilde, K., Wang, H., Lake, V., Holden, P., Middelberg, A.P., He, L., Duff, A., 2012, High yield expression and efficient purification of deuterated human protein galectin-2, Food And Bioproducts Processing [P], vol 90, issue C3, The Institution of Chemical Engineers, Rugby UK, pp. 563-572.
  • Dimitrijev-Dwyer, M., He, L., James, M., Nelson, A., Wang, L., Middelberg, A.P., 2012, The effects of acid hydrolysis on protein biosurfactant molecular, interfacial, and foam properties: pH responsive protein hydrolysates, Soft Matter [P], vol 8, issue 19, Royal Society of Chemistry, Cambridge UK, pp. 5131-5139.
  • Liu, J., Wang, B., Hartono, S., Liu, T., Kantharidis, P., Middelberg, A., Lu, G., He, L., Qiao, S., 2012, Magnetic silica spheres with large nanopores for nucleic acid adsorption and cellular uptake, Biomaterials [P], vol 33, issue 3, Elsevier Ltd, Oxford UK, pp. 970-978.
  • Hartono, S.B., Gu, W., Kleitz, F., Liu, J., He, L., Middelberg, A.P., Yu, C., Lu, G.Q., Qiao, S.Z., 2012, Poly-L-lysine functionalized large pore cubic mesostructured silica nanoparticles as biocompatible carriers for gene delivery, Acs Nano [P], vol 6, issue 3, American Chemical Society, Washington DC USA, pp. 2104-2117.

2011

  • Ding, Y., Chuan, Y., He, L., Middelberg, A., 2011, Dispersive mixing and intraparticle partitioning of protein in size-exclusion chromatographic refolding, Journal of Chromatography A [P], vol 1218, issue 47, Elsevier Science BV, Netherlands, pp. 8503-8510.
    He, L., Onaizi, S., Dimitrijev-Dwyer, M., Malcolm, A., Shen, H., Dong, C., Holt, S., Thomas, R.K., Middelberg, A., 2011, Comparison of positional surfactant isomers for displacement of rubisco protein from the air-water interface, Journal of Colloid and Interface Science [P], vol 360, issue 2, Elsevier, USA, pp. 617-622.
  • Liu, F., Dong, X., He, L., Middelberg, A., Sun, Y., 2011, Molecular insight into conformational transition of amyloid beta-peptide 42 Inhibited by (-)-epigallocatechin-3-gallate probed by molecular simulations, Journal of Physical Chemistry C [P], vol 115, issue 41, American Chemical Soc, Washington DC USA, pp. 11879-11887.
  • Zhao, C., He, L., Qiao, S., Middelberg, A., 2011, Nanoparticle synthesis in microreactors, Chemical Engineering Sciences [P], vol 66, issue 7, Pergamon-Elsevier Science Ltd, Oxford UK, pp. 1463-1479.

2010

  • Ding, Y., Chuan, Y.P., He, L., Middelberg, A.P., 2010, Modeling the competition between aggregation and self-assembly during virus-like particle processing, Biotechnology And Bioengineering [P], vol 107, issue 3, Wiley-Blackwell, Hoboken NJ USA, pp. 550-560.
  • He, L., Wang, H., Garamus, V., Hanley, T., Lensch, M., Gabius, H., Fee, C., Middelberg, A.P., 2010, Analysis of monoPEGylated human galectin-2 by small-angle X-ray and neutron scattering: concentration dependence of PEG conformation in the conjugate, Biomacromolecules [P], vol 11, issue 12, American Chemical Society, Washington DC USA, pp. 3504-3510.
  • Onaizi, S.A., He, L., Middelberg, A.P., 2010, The construction, fouling and enzymatic cleaning of a textile dye surface, Journal of Colloid and Interface Science [P], vol 351, issue 1, Academic Press Inc Elsevier Science, San Diego CA USA, pp. 203-209.

2009

  • He, L., Andre, S., Garamus, V., Siebert, H., Chi, C., Niemeyer, B., Gabius, H., 2009, Small angle neutron scattering as sensitive tool to detect ligand-dependent shape changes in a plant lectin with beta-trefoil folding and their dependence on the nature of the solvent, Glycoconjugate Journal [P], vol 26, issue 1, Springer, Netherlands, pp. 111-116.
  • He, L., Malcolm, A., Dimitrijev, M., Onaizi, S., Shen, H., Holt, S., Dexter, A., Thomas, R., Middelberg, A., 2009, Cooperative tuneable interactions between a designed peptide biosurfactant and positional isomers of SDOBS at the air-water interface, Langmuir [P], vol 25, issue 7, American Chemical Society, USA, pp. 4021-4026.
  • Onaizi, S.A., He, L., Middelberg, A.P., 2009, Proteolytic cleaning of a surface-bound rubisco protein stain, Chemical Engineering Sciences [P], vol 64, issue 17, Pergamon-Elsevier Science LTD, Oxford UK, pp. 3868-3878.
  • Onaizi, S.A., He, L., Middelberg, A.P., 2009, Rapid screening of surfactant and biosurfactant surface cleaning performance, Colloids and Surfaces B: Biointerfaces [P], vol 72, issue 1, Elsevier Science BV, Netherlands, pp. 68-74.
  • Wang, H., He, L., Lensch, M., Gabius, H., Fee, C., Middelberg, A.P., 2009, Biomolecular engineering of human lectin galectin-2, Journal Of Bioscience And Bioengineering [P], vol 108, issue 1, Soc Bioscience Bioengineering Japan, Osaka Japan, p. S61.

2008

  • Ding, Y., He, L., Middelberg, A.P., 2008, Dispersion-enhanced chromatography refolding of denatured protein, Chemical Engineering Sciences [P], vol 63, issue 17, Pergamon-Elsevier Science Ltd, Oxford UK, pp. 4333-4341.
  • Kubler, D., Hung, C., Dam, T., Kopitz, J., Andre, S., Kaltner, H., Lohr, M., Manning, J., He, L., Wang, H., Middelberg, A.P., Brewer, C., Reed, J., Lehmann, W., Gabius, H., 2008, Phosphorylated human galectin-3: Facile large-scale preparation of active lectin and detection of structural changes by CD spectroscopy, Biochimica et Biophysica Acta - General Subjects [P], vol 1780, issue 4, Elsevier Science BV, Netherlands, pp. 716-722.
  • Middelberg, A., He, L., Dexter, A., Shen, H., Holt, S., Thomas, R., 2008, The interfacial structure and Young's modulus of peptide films having switchable mechanical properties, Journal of the Royal Society Interface [E], vol 5, issue 18, The Royal Society Publishing, UK, pp. 47-54.
  • Wang, H., He, L., Lensch, M., Gabius, H., Fee, C., Middelberg, A.P., 2008, Single-site cys-substituting mutation of human lectin galectin-2: modulating solubility in recombinant production, reducing long-term aggregation, and enabling site-specific monoPEGylation, Biomacromolecules [P], vol 9, issue 11, American Chemical Soc, Washington DC USA, pp. 3223-3230.