2012 HDR students

In 2012, Central Clinical School (CCS), in association with Alfred Health, the Burnet and BakerIDI research institutes, had approximately 120 postgraduate students undertaking medical research in a wide variety of subject areas, ranging from basic research to translational clinical settings.  To see students in particular departments, click on the department links below.

Department

Completed students

For details of

2012 postgraduate symposium presenters

2012 CCS postgraduate symposium speakers

Pictured left to right at the 5 October 2012 Postgraduate symposium hosted by Central Clinical School: Dr Kirk Kee, Tara Bull, Be'eri Ni'ego, Christina Chang, Jie Yu Chung, Jay Jha, Amit Joglekar, Eric Tan, Gabriela Khoury, Jessica Biesiekierski, Nigel Rogasch, Sarah Charnaud, Fiona Brown, Perdita Cheshire, Dani Michell, Sarah Hellewell, Karina Huynh, Kai Syin Lee, Miriel Ho. For details, see 5 October 2012 PhD symposium booket

ACBD

PhD students

Ms Amanda E-Ling Au
Investigating the effects of platelet-released factors (PRFs) on the brain

Dr Agatino Calogero
Discovery and analysis of new therapeutic targets for the treatment of multiple Myeloma

Ms Maria Daglas
Investigating the long term effects of TBI on the immune and fibrinolytic system.

Mr Thomas Fulford
The role of the NFkB transcription factor RelA in the function and homeostasis of CD4+ regulatory T

Dr Andrew Guirguis
Apoptosis and its regulation in myelodysplasia - using basic mouse models and human samples.

Ms Miriel Shu Hui Ho
The bone and bone marrow interface and its relationship to haematopoiesis

Mr Zane Kaplan
Determining the role of GPIb binding to thrombin specifically pertaining to its effect on fibrin generation and impact on leukocyte - platelet interaction

Ms Hui Peng Lim
Roles of the NF-kB transcription factors in Acute Myeloid Leukaemia

Ms Bernadine Gueh Cheng Lu
Structural and functional analysis of the interaction of plasmin lysine binding sites with antiplasmin C-terminus

Mr James David McFadyen
PI3 Kinase Inhibitors as adjunct thrombolytic therapies

Ms Emily Nicholls
Heat shock proteins (HSP) and their role in the resistance of bone marrow cancer cells to standard and novel chemotherapeutic strategies

Mr Be'eri Niego
Effects of tissue-type plasminogen activator on the structure and function of the blood-brain barrier in health and disease

Ms Sewa Rijal
Prognostic significance of phosphoinositide signalling in acute myeloid leukaemia

Mr Tse-Chieh Teh
The role of osteopontin (Opn) in acute myeloid leukaemia (AML) and its feasibility as a drug target

Masters Student

Ms Anna Kalff
Multiple myeloma- strategies to predict outcomes in the era of novel anti-myeloma therapies

Allergy, Immunology and Respiratory medicine (AIRmed)

PhD Students

Ms Jodie Abramovitch
Influence of food processing on the allergic immune response to allergens of crustacean species

Ms Tara Bull
CCSP as a biomarker post lung transplantation: genetic predisposition, abundance and function

Ms Kathryn Hackman
Risk factors for diabetes and vascular disease after lung transplantation: focus on CMV infection

Dr Kirk Keh Kee
The effects of heart failure on the lung

Ms Aislin Meehan
Investigating the function of natural killer cells during Immunological responses following lung transplantation

Ms Rohimah Mohamud
Investigating the effects of environmental stimuli on regulatory T cells (Tregs) in the lung

Ms Louise Rowntree
Does anti-viral T cell cross-reactivity reach clinical significance in human lung transplantation

Mr Jeremy Wrobel
Pulmonary hypertension in chronic obstructive pulmonary disease.

Baker IDI Heart and Diabetes Institute

PhD Students

Mr Micah Lee Burch
A novel link between G-protein coupled receptors and serine/theonline kinase receptors in the regulation of proteoglycan synthesis in vascular smooth muscle

Mr Wayne Childs
Novel metabolic actions of HDL with therapeutic potential for type 2 diabeties

Mr Michael Christopher
Dyslipidaemia resulting from obesity is a major contributor to the onset and progression of Type 2 diabetes.

Miss Elyse Di Marco
Role of inflammation in diabetes-associated atherosclerosis

Dr Philipp Diehl
New diagnostic and therapeutic strategies in thrombosis and inflammation.

Dr Nay Min Htun
Monomeric CRP as Inflammatory Mediator and Therapeutic Target in Acute Coronary Syndrome

Ms Karina Huynh
Role of antioxidant and PE3K(p110a) approaches for rescuing diabetic cardiomyopathy.

Mr Jay Chandra Jha
The impact of diabetes induced oxidative stress and oxidant mediated vascular and renal injury

Mr Anmar Anwar Khan
High density lipoprotein (HDL) composition and functionality in type 2 diabetes

Mr Sebastian Lunke
Epigenetic regulation of the human survival of motor neuron gene in spinal muscular atrophy.

Mr Prabhu Mathiyalagan
Cardiac ventricular chambers are epigenetically distinguishable

Mr Aaron McClelland
MicroRNA-21 in diabetic nephropathy: a multifaceted, pathological factor

Mr Ashish Kumar Narayan Nair
Antifungal drugs can affect the immune fuction of T, natural killer and dendritic cells

Ms Gulcan Sarila
Set 7 as an appropriate target to reduce the burden of diabetic vascular and renal complications

Mr Mansur Shmela
Deciphering the role of pluripotency factors (OCT4 and SOX2) in the regulation of genomic imprinting of the human 11p15 IGF2/H19 ICR1 domain

Ms Natasha Tuano
Epigenetic basis for persistence of hyperglycemic variability in mouse embryonic stem cells.

Mr David White
Macrophage Migration Inhibitory Factor (MIF): Pathological and therapeutic significance in post-myocardial infarct inflammation

Burnet Institute

PhD Students

Ms Sarah Charnaud
Supporting protein export in Plasmodium falciparum: A novel HSP70

Mr Brendan Elsworth
Characterisation of the Plasmodium falciparum translocon protein PTEX150

Ms Janet Gare
Antiretroviral therapy in Papua New Guinea: biological and social factors contributing to treatment outcome in HIV infected individuals

Mrs Siti Mohd Hanafiah
Dimeric IgA and cell wall components of M. tuberculosis as tools in point-of-care diagnostics

Department of Gastroenterology

PhD Students

Dr Mayur Garg
The renin-angiotensin system and Vitamin D in inflammatory bowel disease: novel mechanisms and manag

Miss Emma Halmos
Management of irritable bowel syndrome and enteral nutrition associated diarrhoea by reducing intake of poorly absorbed sugars.

Ms Sreepurna Malakar
Understanding food hypersensitivity: identifying clinical targets and biomarkers of non-coeliac gluten intolerance

Mr Evan Newnham
Shifting treatment paradigms in newly diagnosed coeliac disease
Ms Simone Peters
The role of wheat gluten in the genesis of gastrointestinal symptoms and fatigue in NCGI patients

Dr Hamish Philpott
The significance or aeroallergens in eosinophilic esophagitis

Department of Immunology

PhD Students

Mr Jie-Yu Chung
Mechanisms of tolerance following ectopic autoantigen expression

Ms Devy Deliyanti
An evaluation of aldosterone's pathogenic role in the ischemic and diabetic retina

Ms Maria Demaria
The function of leucocyte-specific tetraspanins CD37 and CD53 in the immune system.

Mr Benjamin Fancke
Dendritic cells: development, tolerance and immunity. A novel cross-species study.

Mr Qian Gao
Developing a therapeutic nano-vaccine against ovarian cancer

Ms Chindu Govindaraj
The role of TMFR2+ regulatory T cells in cancer

Ms Elisha Horat
The role of NFκB1 in lymphocyte homeostasis and autoimmunity

Mr Abhirup Jayasimhan
Probing the pathogenesis of type 1 diabetics by studying the role of MHC class 1 expression on pancreatic ductal lineage cells

Mr Amit Joglekar
Mechanisms of tolerance following genetic manipulation and transfer of bone marrow stem cells

Ms Eleanor Livingston Jones
A reserve genetic approach to tetraspanin CD82

Ms Indzi Katik
Regulation of telomerase activity and telomere remodeling in lymphocytes

Ms Ying Ying Kong
Effects of cancer cells on the cells of the dendritic cell lineage

Mr Jiaze Lee
Roles of CDA1 in vascular diseases

Mr Mutsa Madondo
Study of the principles for the design of optimal nanoparticle based cancer vaccines

Ms Kirsten Morris
Towards developing cytokines as therapeutics for infections in pigs

Mr Zeyad Nasa
The induction of immune tolerance through genetic manipulation of haematopoietic stem cells

Ms Pin Shie Quah
The roles of BAFF, B , NK and NKT cells in solid tumours

Mr Dean Talia
The role of the adaptive immune system in the formation and progression of retinopathy

Dr Fabien Vincent
Role of BAFF and the T-independent innate immune system in lupus pathogenesis

Ms Leanne Wang
Development of cancer immunotherapy using gene-engineered T cells in a self-antigen mouse model

Miss Yih Teng (Felicia) Yap
The Contribution of AGEs and the Receptors to Beta Cell Dysfunction

Ms Cai (Carol) Zhang
The possible mechanism of hematopoietic stem-cell transfer on the immune tolerance in NOD mice

Ms Pam Tong Zhu
Prorenin and prorenin receptor: Mechanisms of action in diabetic retinopathy

Department of Infectious Diseases

PhD Students

Dr Christina Chang
Immunopathogenesis and diagnosis of cryptococcal-associated immune restoration disease in people with HIV

Ms Gabriela Khoury
Viral reservoirs- role of naive T-cells in the pathogenesis of T-Cell decline and long term persistence of HIV infection

Ms Nitasha Kumar
Dendritic Cell (DC) induced HIV latency in Resting CD4 T-Cells

Dr Katherine Langan
A prospective, randomised, double-blind trial of extended- versus bolus- infusion -lactam

Mr James Mcmahon
Social and behavioural factors associated with poor outcomes in patients infected with HIV on antiretroviral therapy

Ms Janine Trevillyan
Pathogenesis and prevention of cariodvascular disease in HIV positive patients

Ms Fiona Wightman
The use of Histone Deacetlyase inhibitors to reverse HIV-1 latency

Dr Michelle Yong
Detection and clinical significance of CMV specific T cell immunity following transplantation

Monash Alfred Psychiatry research centre (MAPrc)

PhD Students

Dr Sarah Abrahamson
Sensory aspects of adult high-functioning Autism spectrum disorders

Miss Jessica Bell
Studying neurobiological predictors of antidepressant response to Transcranial Magnetic Stimulation

Mrs Natalia Contreras
An investigation of semantic memory in first-episode psychosis

Ms Jodie Feil
Inhibition in major depressive disorder

Ms Sacha Filia
Monitoring and improving outcomes and quality of life with severe schizophrenia - A biopsychosocial approach

Ms Amity Green
Investigating the effects of glycine on cognition in schizophrenia

Mr Phillip Hall
A Neuroeconomic investigation into clinical depression and anhedonia

Miss Melissa Kirkovski
Neural connectivity in autism spectrum disorders

Mr Phillip Cheuk Fung
Law Investigating perceptual rivalry as a psychiatric biomarker

Mr Tony Letic
Investigating the neural correlates of brain stimulation on neurocognition.

Ms Erica Neill
Investigating the neural basis of memory impairments in schizophrenia

Mr Nigel Rogasch
The relationship between depression and dysfunctional coordination of neural activity as measured by EEG Activity

Mr Gershon Spitz
Developing a biopsychosocial model to explain the relationship between organic, cognitive, psychiatric, and functional outcomes following traumatic brain injury (TBI)

Mr Eric Tan
Speech disturbances and quality of life in schizophrenia

Department of Medicine

PhD Students

Mr Michael Cangkrama
Analysis of the grainyhead-like genes in mammalian development and disease

Dr Luke Chen
Methecillin-resistant staphyloccoccus aureus (MRSA) bloodstream and surgival site infections in community hospitals: Epidemilogy, risk factors, and patient outcomes

Ms Perdita Cheshire (Van Cleef / Roet Centre for Nervous Diseases)
Is dysfunction of the serotonin system responsible for L-DOPA induced dyskinesias in Parkinson's disease?

Dr Andris Ellims
Ventricular remodelling in cardiomyopathy - impact on ventricular physiology and cardiovascular outcomes

Ms Sarah Hellewell (National Trauma Research Institute – NTRI)
Pathophysiology and therapeutic strategies for the treatment of traumatic brain injury: investigating the role of erythropoietin

Dr Leah Maree Iles
Myocardial fibrosis and heart failure

Ms Gabriela Khoury
Viral reservoirs- role of naive T-cells in the pathogenesis of T-Cell decline and long term persistence of HIV infection

Mr Ishant Khurana
Chromatin immunopurification strategies for the application and standardisation of next generation sequencing

Dr Matthew Kitson
A study of the relationship between vitamin D status and outcomes of chronic liver disease

Ms Nitasha Kumar
Dendritic Cell (DC) induced HIV latency in Resting CD4 T-Cells

Dr Katherine Langan
A prospective, randomised, double-blind trial of extended- versus bolus- infusion -lactam

Ms Kai Syin Lee
Analysis of Inositol compounds as a therapeutic intervention in squamous cell carcinoma (SCC)

Ms Evelyn Lindsay (Van Cleef / Roet Centre for Nervous Diseases)

Cerebellar disease: Exploring the application, reliability and validity of a diagnostic instrument for quantifying ataxia of the upper limbs

Mr James Hamilton McMahon
Social and behavioural factors associated with poor outcomes in patients infected with HIV on antiretroviral therapy

Ms Danielle Lisa Li Mei Michell
Hypertension induced inflammation in the endothelium:  The signalling pathways involved.

Ms Amber Moore  (Centre for Ethics and Medicine in Society - CEMS)
Philosophical and professional aspects of Chinese medicine

Ms Lina Nheu (CEMS)
Effects of Androgens on Cardiovascular Cell Physiology: Events relevant to Atherogenesis

Dr Dion Ashley Stub
Improving prognosis in Out Of Hospital cardiac arrest utilising circulatory support

Ms Janine Trevillyan
Pathogenesis and prevention of cariodvascular disease in HIV positive patients

Miss Melanie Voevodin (CEMS)
Can dietitians turn around the obesity epidemic?

Ms Fiona Wightman
The use of Histone Deacetlyase inhibitors to reverse HIV-1 latency

Dr Michelle Karen Yong
Detection and clinical significance of CMV specific T cell immunity following transplantation

MD Student

Mr Antony Friedman
Use of allopurinol in azathioprine/6-MP non-responders to optimise 6-TGN and improve outcomes

MD (Supervised) Students

Ms Angeline Shu-Lin Leet
Myocardial fibrosis and function after heart transplantation- factors involved in myocardial collagen turnover and relationship to clinical symptoms and outcome.

Dr Eileen Merriman
Management of distal DVT-A  treatment paradigm


Department of Surgery & NTRI

PhD Students

Mr Philip Lewis
Methodological considerations in cerebral autoregulation assessment

Mr David Oehme
Lumbar disc repair and regeneration

Dr Elena Shek
Supporting the best care based on the best available research in neurotrauma

Mr Hugh Stephens
The potential for organ donation in Australia - what is really possible?

Ms Emma Tavender
Management of mild traumatic brain injury in the emergency department: Barriers, enablers to evidence uptake and development of an intervention to facilitate best practice and improve patient outcomes

Ms Juliana Van der Nerwe
Exercise haemodynamics in patients with a centrifugal (non-pulsatile) flow pump and the need for a physiological controller to adjust pump speed during exercise

MD (Supervised) Student

Mr Jin Wee Tee
Predictors of functional outcomes of patients with traumatic spine fractures

2012 Completed students

PhD

ACBD

Ms Rachael Borg
Investigation into the interaction between tissue-type plasminogen activator and dead neuronal cells

Ms Katherine Monaghan
Microenvironmental factors impacting on multiple myeloma drug resistance

Ms Jessica Mountford
Defining the cellular functions of class II P13Ks

Baker IDI

Ms Sacha Mei Leng Khong
The role of arginase I and II in the vasculature

Ms Poay Sian Lee
Immunopathogenesis and diagnosis of cryptococcal-associated immune restoration disease in people with HIV

Department of Gastroenterology

Ms Jessica Biesiekierski
Understanding the role of gluten in the genesis of gastrointestinal symptoms in individuals who do not have coeliac disease

Department of Immunology

Mr Craig Nicholls
The molecular regulation of telomeres and telomerase

Mr Louis Meng-Chin Tsai
Novel mechanisms of T and B lymphocyte homeostasis and differentiation

Department of Medicine

Ms Dilinie Herbert
Attitudes, beliefs and experiences of genetic testing: A study of the haemophilia community.

Dr Mukherjee Swati
Role of oxidative stress in coronary artery disease and its clinical presentations

Mr Gregor Lichtfuss
Signals through ITAM

Mr Michael Roche
Understanding HIV-1 entry: insights through the envelope protein

Ms Emma Tippett
Contribution of moncyte subset to HIV-1 viral reservoirs

MD

Dr Christine Ball
A history of anaesthesia