2013 HDR students

2013 CCS Postgraduate Students

Central Clinical School (CCS), in association with Alfred Health, the Burnet and BakerIDI research institutes, had 154 postgraduate students enrolled during 2013, who undertook medical research in a wide variety of subject areas, ranging from basic research to translational clinical settings. To see students in particular departments, click on the department links below.

Archive

Department

Completed students

For details of

2013 new PhD students

2013 new PhD students

L-R: PhD students CK Yao, Hui Peng Lim, Shanzana Khan, Ting Ting Cao, Rodney Anderson, CCS Postgraduate Coordinator Professor Rob Medcalf, Ashlee Murphy, Simone Peters, Marina Iacovou, Sreepurna Malakar

Australian Centre for Blood Diseases (ACBD)

Dr Saheb Al-Daher 
Studying platelet prothrombotic mechanisms in diabetes mellitus

Ms Reem Alzayer 
The role of ACEII in both diabetic nephropathy and retinopathy.

Dr Sung Chiu 
Defining the role of LYL1 and NF-kappaB in T-cell acute lymphoblastic leukemia

Ms Maria Daglas 
Investigating the long term effects of TBI on the immune and fibrinolytic system

Mr Tom Fulford 
The role of the NFkB transcription factor RelA in the function and homeostasis of CD4+ regulatory T

Dr Andrew Guirguis 
Apoptosis and its regulation in myelodysplasia - using basic mouse models and human samples

Ms Miriel Ho 
The bone and bone marrow interface and its relationship to haematopoiesis

Ms Anna Kalff 
Multiple myeloma- stratergies to predict outcomes in the era of novel anti-myeloma therapies

Mr Zane Kaplan 
Determining the role of GPIb binding to thrombin specifically pertaining to its effect on fibrin generation and impact on leukocyte - platelet interaction

Ms Hannah Lee 
Defining the roles of protease-activated receptors in thrombosis

Ms Hui Lim 
Roles of the NF-kB transcription factors in Acute Myeloid Leukaemia

Ms Cindy Lin  
The role of phosphatase CD45 in determining the signalling, proliferation and therapeutic drug sensitivities of human myeloma cells

Ms Bernadine Lunke 
Structural and functional analysis of the interaction of plasmin lysine binding sites with antiplasmin C-terminus

Mr James Mcfadyen 
PI3 Kinase Inhibitors as adjunct thrombolytic therapies

Ms Emily Nicholls 
Heat Shock Proteins (Hsp) And Their Role In The Resistance Of Bone Marrow Cancer Cells To Standard And Novel Chemotherapeutic Strategies

Mr Be'Eri Niego 
Effects of tissue-type plasminogen activator on the structure and function of the blood-brain barrier in health and disease

Mr  Jianlin Qiao 
Shedding of platelet receptors in health and disease

Ms Sewa Rijal 
Prognostic significance of phosphoinositide signalling in acute myeloid leukaemia

Ms Ioanna Savvidou 
Role of  Wnt pathway dysregulation in Multiple Myeloma (MM)

Mr Tse-Chieh The 
The role of osteopontin (Opn) in acute myeloid leukaemia (AML) and its feasibility as a drug target

Master of Biomedical Science

Mr Beldon Mado 
Pelger Huet and Alder Reilly Anomalies in Papua New Guinea

Master of Philosophy

Dr Wai Chow 
Exploring the potential of epigenetic therapies in Multiple Myeloma

Masters by Research

Dr Peter Tan 
Exploring novel molecular targets for the therapy of acute myeloid leukaemia

Department of Allergy, Immunology and Respiratory medicine (AIRmed)

Ms Jodie Abramovitch 
Influence of food processing on the allergic immune response to allergens of crustacean species

Ms Rohimah Mohamud 
Investigating the effects of environmental stimuli on regulatory T cells (Tregs) in the lung

Dr Kathryn Hackman 
Risk factors for diabetes and vascular disease after lung transplantation: focus on CMV infection

Dr Kirk Kee 
The effects of heart failure on the lung

Dr Katherine Langan 
Continuous-infusion anti-pseudomonal beta-lactams for the treatment of acute, infective pulmonary exacerbations in cystic fibrosis: a prospective randomised controlled trial

Ms Aislin Meehan 
Investigating the function of natural killer cells during Immunological responses following lung transplantation

Ms Louise Rowntree 
Does anti-viral T cell cross-reactivity reach clinical significance in human lung transplantation

Mr Jeremy Wrobel 
Pulmonary hupertension in chronic obstructive pulmonary disease

Baker/IDI Heart and Diabetes Institute

Mr Wayne Childs 
Novel metabolic actions of HDL with therapeutic potential for type 2 diabeties

Dr Mei Choy 
Stabilizing unstable atheromas by inhibiting activity of matrix metalloproteinases (MMP) using zinc

Mr Michael Christopher 
Dyslipidaemia resulting from obesity is a major contributor to the onset and progression of Type 2 diabetes

Mr Paddy Dempsey 
Sedentary behaviour: Dose response & implications toward cardio-metabolic risk & health outcomes

Miss Elyse Di Marco 
Role of inflammation in diabetes-associated atherosclerosis

Mr Steven Fernandez 
L-arginine transport in obesity dependent hypertension

Mr Daniel  Fineberg 
The epigenetic dysregulation of obesogenic hypothalamic genes by maternal diet

Ms Brooke Elyse Harcourt 
RAGE, adipose derived estrogens and dietary AGEs; interactions in obesity induced kidney disease

Dr Nay Htun 
Monomeric CRP as Inflammatory Mediator and Therapeutic Target in Acute Coronary Syndrome

Ms Karina Huynh 
Role of antioxidant and PE3K(p110a) approaches for rescuing diabetic cardiomyopathy

Mr Jay Jha 
The impact of diabetes induced oxidative stress and oxidant mediated vascular and renal injury

Mr Antony Kaspi 
The Identification of Clinically Relevant Therapies for Human Disease via High Throughput Sequencing

Mr Samuel Keating 
The role of epigenetic chomatin remodelling in the expression of genes relevant to diabetic nephropathy

Mr Anmar Khan 
High density lipoprotein (HDL) composition and functionality in type 2 diabetes

Mr Shanzana Khan 
A new approach to prevention of acute kidney injury after cardiac surgery

Mr Man  Lee 
The Role of High Density Lipoproteins in Macrophage Polarization

Mr Jiaze Li 
Roles of CDA1 in vascular diseases

Mr Sebastian Lunke 
Epigenetic regulation of the human survival of motor neuron gene in spinal muscular atrophy

Mr Prabhu Mathiyalaga  
Cardiac ventricular chambers are epigenetically distinguishable

Mr Aaron McClelland 
microRNA-21 in Diabetic Nephropathy: a multifaceted, pathological factor

Ms Ashlea Murphy 
Composition of lipoproteins, their effect on vascular function and contribution to atherosclerosis

Mr Ashish Nair 
Antifungal drugs can affect the immune fuction of T, natural killer and dendritic cells

Ms Jenny Ooi 
The role of chromatin modifiers and DNA methylation in transcription regulation during cardiac hypertrophy

Miss Hannah Pearce 
Preventing atherosclerosis development with a targeted gene therapy to inhibit VCAM-1

Mr Gulcan Sarila 
Set 7 as an appropriate target to reduce the burden of diabetic vascular and renal complications

Mr Mansur Shmela 
Regulation of Genomic Imprinting at the Human 11p15 Region

Ms Natasha Tuano 
Epigenetic basis for persistence of hyperglycemic variability in mouse embryonic stem cells

Mr David White 
Macrophage Migration Inhibitory Factor (MIF): Pathological and therapeutic significance in post-myocardial infarct inflammation

Miss Yih Yap 
The Contribution of AGEs and the Receptors to Beta Cell Dysfunction

Miss Kristina Zaldivia 
Investigations into the effects of renal denervation on monocyte activation in hypertension

Burnet Institute jointly with Departments of Immunology & Medicine PhD students

Ms Sarah Charnaud
Supporting protein export in Plasmodium falciparum: A novel HSP70

Mr Brendan Elsworth
Characterisation of the Plasmodium falciparum translocon protein PTEX150

Ms Janet Gare
Antiretroviral therapy in Papua New Guinea: biological and social factors contributing to treatment outcome in HIV infected individuals

Mrs Siti Mohd Hanafiah
Dimeric IgA and cell wall components of M. tuberculosis  as tools in point-of-care  diagnostics

Department of Gastroenterology

Dr Mayur Garg 
The Renin-Angiotensin System and Vitamin D in Inflammatory Bowel Disease: Novel Mechanisms and Manag

Dr Ilana Gory 
A Prospective Study Of The Pathogenesis And Management Of Minimal Hepatic Encephalopathy In Chronic

Miss Emma Halmos 
Management of irritable bowel syndrome and enteral nutrition associated diarrhoea by reducing intake of poorly absorbed sugars

Ms Marina Iacovou 
Possible role of poorly absorbed short chain carbohydrates (FODMAPs) in the genesis of infant colic

Ms Sreepurna Malakar 
The role of naturally occuring dietary salicylates in Irritable Bowel Syndrome (IBS)

Mr Evan Newnham 
Shifting treatment paradigms in newly diagnosed coeliac disease

Ms Simone Peters 
The role of wheat gluten in the genesis of gastrointestinal symptoms and fatigue in NCGI patients

Dr Hamish Philpott 
The significance or aeroallergens in eosinophilic esophagitis

Ms Caroline Tuck 
Adjunct therapy to the Low FODMAP dietary management of Irritable Bowel Syndrome

Ms Chu Yao 
Understanding the role of protein fermentation in regulating large bowel fermentation and therapeutic implications for gastrointestinal conditions

Masters student

Dr Salena Ward
Investigation of Pancreatic Exocrine Function in Patients Undergoing Resection of Upper-Gastrintestinal Cancer

Department of Immunology

Mr Christopher Chan  
The role of NK cell receptors in immunity and cancer

Mr Jie-Yu Chung 
Mechanisms of tolerance following ectopic autoantigen expression

Ms Maria Demaria 
The function of leucocyte-specific tetraspanins CD37 and CD53 in the immune system

Mr Benjamin Fancke 
Dendritic cells: development, tolerance and immunity. A novel cross-species study

Mr Qian Gao 
Developing a therapeutic nano-vaccine against ovarian cancer

Mr Timothy Gottschalk 
Identifying and targeting signaling pathways in lupus using a clinically relevant model

Ms Chindu Govindaraj 
The role of TNFR2+ regulatory T cells in cancer

Mr Andrew Guy 
Assessing unstructured proteins in Plasmodium falciparum and their importance in humoral immunity

Ms Elisha Horat 
The role of NFκB1 in lymphocyte homeostasis and autoimmunity

Mr Abhirup Jayasimhan 
Probing the pathogenesis of type 1 diabetics by studying the role of MHC class 1 expression on pancreatic ductal lineage cells

Mr Amit  Joglekar 
Mechanisms of tolerance following genetic manipulation and transfer of bone marrow stem cells

Ms Eleanor Jones 
A reserve genetic approach to tetraspanin CD82

Ms Indzi Katik 
Regulation of telomerase activity and telomere remodeling in lymphocytes

Ms Ying Kong 
Effects of cancer cells on the cells of the dendritic cell lineage

Mr Mutsa Madondo 
The role of TNFR2 T cells in human disease

Ms Kirsten Morris 
Towards developing cytokines as therapeutics for infections in pigs

Mr Zeyad Nasa 
The induction of immune tolerance through genetic manipulation of haematopoietic stem cells

MS Hong-An Thi Nguyen 
The activin A/follistatin axis in regulation of airway inflammation and remodelling using a murine model of chronic allergic asthma

Ms Pin Shie Quah 
The roles of BAFF, B , NK and NKT cells in solid tumours

Mr Damien Saulep-Easton 
Re-evaluating Chronic Lymphocytic Leukaemia Pathogenesis: implications for therapy

Mr Dean Talia 
The role of the adaptive immune system in the formation and progression of retinopathy

Dr Fabien Vincent 
Role of BAFF and the T-independent innate immune system in lupus pathogenesis

Ms Kirsty Wilson 
Enhancing the immune response to vaccines using nanoparticles

Ms Cai Zhang 
The possible mechanism of hematopoietic stem-cell transfer on the immune tolerance in NOD mice

Ms Pam Zhu 
Prorenin and prorenin receptor: Mechanisms of action in diabetic retinopathy

Department of Infectious Diseases

Ms Gabriela Khoury 
Viral reservoirs- role of naive T-cells in the pathogenesis of T-Cell decline and long term persistence of HIV infection

Ms Nitasha Kumar 
Dendritic Cell (DC) induced HIV latency in Resting CD4 T-Cells

Mrs Tanya Millard 
The development and evaluation of an online self management program for men living with HIV

Dr Kasha Singh 
Dissecting mechanisms of liver disease progression in HIV-Hepatitis B co-infection

Ms Janine Trevillyan 
Pathogenesis and prevention of cariodvascular disease in HIV positive patients

Ms Fiona Wightman 
The use of Histone Deacetlyase inhibitors to reverse HIV-1 latency

Dr Michelle Yong 
Detection and clinical significance of CMV specific T cell immunity following transplantation

Dr Chang Christina 
Immunopathogenesis and diagnosis of cryptococcal-associated immune restoration disease in people with HIV

Department of Medicine

Ms Judith Allen-Graham (Van Cleef) 
Inhibition of APP and APLP2 using siRNA to investigate protein function and Alzheimer's disease

Mrs Amani Alrehaili 
Targeting the Nogo-A receptor (NgR1) signaling mechanism in a model
of multiple sclerosis will limit the degeneration of axons

Ms Tara Bull 
CCSP as a biomarker post lung transplantation: genetic predisposition, abundance and function

Mr Michael Cangkrama 
Analysis of the grainyhead-like genes in mammalian development and disease

Dr Michael Chapman 
The ethics of decision making at the end of life

Dr Luke Chen 
Methecillin-resistant staphyloccoccus aureus (MRSA) bloodstream and surgival site infections in community hospitals: Epidemilogy, risk factors, and patient outcomes

Ms Danielle Couch 
How is body weight potrayed in three types of contemporary popular Australian media?

Mr Philipp Diehl 
New diagnostic and therapeutic strategies in thrombosis and inflammation

Dr Andris Ellims 
Ventricular remodelling in cardiomyopathy - impact on ventricular physiology and cardiovascular outcomes

Dr Patrick Fiddes 
An evaluation of the educational philosophies of Sir William Osler

Ms Sarah Hellewell (NTRI)
Pathophysiology and therapeutic strategies for the treatment of traumatic brain injury: investigating the role of erythropoietin

Dr Leah Iles 
Myocardial fibrosis and heart failure

Mr Ishant Khurana 
Chromatin immunopurification strategies for the application and standardisation of next generation sequencing

Dr Matthew Kitson 
A study of the relationship between vitamin D status and outcomes of chronic liver disease

Mr Jae Lee 
Targeting the molecular mechanisms of axonal degeneration and de/remyelination in mulitpule sclerosis in multiple sclerosis

Ms Kai Syin Lee 
Analysis of Inositol compounds as a therapeutic intervention in squamous cell carcinoma (SCC)

Ms Evelyn  Lindsay 
Cerebellar disease: Exploring the application, reliability and validity of a diagnostic instrument for quantifying ataxia of the upper limbs

Mr James McMahon 
Social and behavioural factors associated with poor outcomes in patients infected with HIV on antiretroviral therapy

Ms Amber Moore 
Philosophical and professional aspects of Chinese medicine

Ms Lina Nheu 
Effects of Androgens on Cardiovascular Cell Physiology: Events relevant to Atherogenesis

Ms Dion Stub 
Improving prognosis in Out Of Hospital cardiac arrest utilising circulatory support

Ms Melanie Voevodin 
Can dietitians turn around the obesity epidemic?

Ms Perdita Cheshire (Van Cleef)
Is dysfunction of the serotonin system responsible for L-DOPA induced dyskinesias in Parkinson's disease?

DM

Mr Antony Friedman
Use of allopurinol in azathioprine/6-MP non-responders to optimise 6-TGN and improve outcomes

Ms Angeline Leet 
Myocardial fibrosis and function after heart transplantation- factors involved in myocardial collagen turnover and relationship to clinical symptoms and outcome

MD (Supervised) Students

Dr Eileen Merriman
Management of distal DVT-A  treatment paradigm

Master of Philosophy

Mr Guy Marquis
Doubtful knowledge - The intimacy of science and uncertainty in medicine

Monash Alfred Psychiatric Research Centre (MAPrc)

Dr Sarah Abrahamson
Sensory aspects of adult high-functioning Autism spectrum disorders

Mr Rodney Anderson
The neurophysiological mechanisms underlying the therapeutic effects of TMS for TRD

Mr Neil Bailey
The relationship between depression and dysfunctional coordination of neural activity as measured by EEG activity

Ms Tingting Cao
Blood Oxygenation Changes Resulting from Transcranial Magnetic Stimulation of Prefrontal Cortex

Mrs Natalia Contreras
An investigation of semantic memory in first-episode psychosis

Ms Jodie Feil
Inhibition in major depressive disorder

Amity Green 
Investigating the effects of glycine on cognition in schizophrenia

Mr Phillip Hall
A Neuroeconomic investigation into clinical depression and anhedonia

Miss Melissa Kirkovski
Neural connectivity in autism spectrum disorders

Mr Phillip Law
Investigating perceptual rivalry as a psychiatric biomarker

Ms Erica Neil
Investigating the neural basis of memory impairments in schizophrenia

Mr Nigel Rogasch
The relationship between depression and dysfunctional coordination of neural activity as measured by EEG Activity

Mr Gershon Spitz
Developing a biopsychosocial model to explain the relationship between organic, cognitive, psychiatric, and functional outcomes following traumatic brain injury (TBI)

Mr Eric Tan
Speech disturbances and quality of life in schizophrenia

Department of Surgery and NTRI

Mr Philip Lewis
Methodological considerations in cerebral autoregulation assessment

Mr David Oehme
Lumbar disc repair and regeneration

Dr Elena Shek (NTRI)
Supporting the best care based on the best available research in neurotrauma

Ms Emma Tavender (NTRI)
Management of mild traumatic brain injury in the emergency department: Barriers, enablers to evidence uptake and development of an intervention to facilitate best practice and improve patient outcomes

Ms. Juliana Van Der Nerwe
Exercise haemodynamics in patients with a centrifugal (non-pulsatile) flow pump and the need for a physiological controller to adjust pump speed during exercise

MD (supervised)

Mr Jin Wee Tee (NTRI)
Predictors of functional outcomes of patients with traumatic spine fractures

Master of Surgery

Ms Tze Koh 
Use of Vitamin K vs. Clexane Bridging for Reversal of Warfarinisation prior to Surgery

Mr Casey Lo 
Right Ventricular Mechanical Support in Pre-Cardiac Transplant Patients