Department of Immunology Publications 2016

Review articles

Bousquet, J, Farrell, J, Crooks, G, Hellings, P, Bel, EH, Bewick, M, Chavannes, NH, De Sousa, JC, Cruz, AA, Haahtela, T, Joos, G, Khaltaev, N, Malva, J, Muraro, A, Nogues, M, Palkonen, S, Pedersen, S, Robalo-Cordeiro, C, Samolinski, B, Strandberg, T & O'Hehir, RE 2016, 'Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5)' Clinical and Translational Allergy, vol 6, no. 1, 29. DOI: 10.1186/s13601-016-0116-9

Bousquet, J, Hellings, PW, Agache, I, Bedbrook, A, Bachert, C, Bergmann, KC, Bewick, M, Bindslev-Jensen, C, Bosnic-Anticevitch, S, Bucca, C, Caimmi, DP, Camargos, PAM, Canonica, GW, Casale, T, Chavannes, NH, Cruz, AA, De Carlo, G, Dahl, R, Demoly, P, Devillier, P & O'Hehir, RE 2016, 'ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle' Clinical and Translational Allergy, vol 6, no. 1, 47. DOI: 10.1186/s13601-016-0137-4

Jha, JC, Banal, C, Chow, BSM, Cooper, ME & Jandeleit-Dahm, K 2016, 'Diabetes and kidney disease: Role of oxidative stress' Antioxidants and Redox Signaling, vol 25, no. 12, pp. 657-684. DOI: 10.1089/ars.2016.6664

Jutel, M, Agache, I, Bonini, S, Burks, AW, Calderon, M, Canonica, W, Cox, L, Demoly, P, Frew, AJ, O'Hehir, R, Kleine-Tebbe, J, Muraro, A, Lack, G, Larenas, D, Levin, M, Martin, BL, Nelson, H, Pawankar, R, Pfaar, O, Van Ree, R, Sampson, H, Sublett, JL, Sugita, K, Du Toit, G, Werfel, T, Gerth Van Wijk, R, Zhang, L, Akdis, M & Akdis, CA 2016, 'International Consensus on Allergen Immunotherapy II: Mechanisms, standardization, and pharmacoeconomics' Journal of Allergy and Clinical Immunology, vol 137, no. 2, pp. 358-368. DOI: 10.1016/j.jaci.2015.12.1300

Madondo, MT, Quinn, M & Plebanski, M 2016, 'Low dose cyclophosphamide: Mechanisms of T cell modulation' Cancer Treatment Reviews, vol 42, pp. 3-9. DOI: 10.1016/j.ctrv.2015.11.005

O'Hehir AO, R, Prickett, SR & Rolland, JM 2016, 'T cell epitope peptide therapy for allergic diseases' Current Allergy and Asthma Reports, vol 16, no. 2, 14, pp. 1-9. DOI: 10.1007/s11882-015-0587-0

Journal articles

Abramson, MJ, Kaushik, S, Benke, GP, Borg, BM, Smith, CL, Dharmage, SC & Thompson, BR 2016, 'Symptoms and lung function decline in a middle-aged cohort of males and females in Australia' International Journal of Chronic Obstructive Pulmonary Disease, vol 11, no. 1, pp. 1097-1103. DOI: 10.2147/COPD.S103817

Abramson, MJ, Matheson, MC, Allen, KJ, Benke, GP, Burgess, JA, Dowty, JG, Erbas, B, Feather, IH, Frith, PA, Giles, G, Gurrin, LC, Garun S, H, Hopper, J, James, AL, Jenkins, MA, Johns, DP, Lodge, CJ, Lowe, AJ, Markos, J, Morrison, SC, Perret, J, Southey, MC, Thomas, PS, Thompson, BR, Wood-Baker, R, Walters, EH & Dharmage, SC 2016, 'Cohort Profile: the Tasmanian Longitudinal Health Study' International Journal of Epidemiology. DOI: 10.1093/ije/dyw028

Beth, SA, Jansen, MAE, Elfrink, MEC, Kiefte-de Jong, JC, Wolvius, EB, Jaddoe, VWV, van Zelm, MC & Moll, HA 2016, 'Generation R birth cohort study shows that specific enamel defects were not associated with elevated serum transglutaminase type 2 antibodies' Acta Paediatrica, vol 105, no. 10, pp. e485-e491. DOI: 10.1111/apa.13533

Buskes, MJ, Harvey, KL, Richards, BJ, Kalhor, R, Christoff, RM, Gardhi, CK, Littler, DR, Cope, ED, Prinz, B, Weiss, GE, O'Brien, NJ, Crabb, BS, Deady, LW, Gilson, PR & Abbott, BM 2016, 'Antimalarial activity of novel 4-cyano-3-methylisoquinoline inhibitors against Plasmodium falciparum: Design, synthesis and biological evaluation' Organic & Biomolecular Chemistry, vol 14, no. 20, pp. 4617-4639. DOI: 10.1039/c5ob02517f

Chevalier, N, Macia, L, Tan, JK, Mason, LJ, Robert, R, Thorburn, AN, Wong, CHY, Tsai, LM, Bourne, K, Brink, R, Yu, D & Mackay, CR 2016, 'The role of follicular helper T cell molecules and environmental influences in autoantibody production and progression to inflammatory arthritis in mice' Arthritis & Rheumatology, vol 68, no. 4, pp. 1026-1038. DOI: 10.1002/art.39481

Chevalier, N, Tan, JK, Mason, LJ, Robert, R, McKenzie, CI, Lim, F, Wong, CH, Macia, L, Thorburn, AN, Russ, BE, Masters, SL & Mackay, CR 2016, 'Avenues to autoimmune arthritis triggered by diverse remote inflammatory challenges' Journal of Autoimmunity, vol 73, pp. 120-129. DOI: 10.1016/j.jaut.2016.06.018

Coughlan, MT, Higgins, GC, Nguyen, T-V, Penfold, SA, Thallas-Bonke, V, Tan, SM, Ramm, G, Van Bergen, NJ, Henstridge, DC, Sourris, KC, Harcourt, BE, Trounce, IA, Robb, PM, Laskowski, A, McGee, SL, Genders, AJ, Walder, K, Drew, BG, Gregorevic, P, Qian, H, Thomas, MC, Jerums, G, Macisaac, RJ, Skene, A, Power, DA, Ekinci, EI, Wijeyeratne, XW, Gallo, LA, Herman-Edelstein, M, Ryan, MT, Cooper, ME, Thorburn, DR & Forbes, JM 2016, 'Deficiency in apoptosis-inducing factor recapitulates chronic kidney disease via aberrant mitochondrial homeostasis' Diabetes, vol 65, no. 4, pp. 1085-1098. DOI: 10.2337/db15-0864

Coughlan, MT, Nguyen, TV, Penfold, SA, Higgins, GC, Thallas-Bonke, V, Tan, SM, Van Bergen, NJ, Sourris, KC, Harcourt, BE, Thorburn, DR, Trounce, IA, Cooper, ME & Forbes, JM 2016, 'Mapping time-course mitochondrial adaptations in the kidney in experimental diabetes' Clinical Science, vol 130, no. 9, pp. 711-720. DOI: 10.1042/CS20150838

Dahl, LCM, Nasa, Z, Chung, J, Niego, B, Tarlac, V, Ho, KCH, Galle, AA, Petratos, S, Alderuccio, FP & Medcalf, RL 2016, 'The influence of differentially expressed tissue-type plasminogen activator in experimental autoimmune encephalomyelitis: Implications for multiple sclerosis' PLoS ONE, vol 11, no. 7, e0158653. DOI: 10.1371/journal.pone.0158653

de Valle, E, Grigoriadis, G, O'Rielly, LA, Willis, SN, Maxwell, MJ, Corcoran, LM, Tsantikos, E, Cornish, JKS, Fairfax, KA, Vasanthakumar, A, Febbraio, MA, Hibbs, ML, Pellegrini, M, Banerjee, A, Hodgkin, PD, Kallies, A, Mackay, F, Strasser, A, Gerondakis, S & Gugasyan, R 2016, 'NF¿B1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells' Journal of Experimental Medicine, vol 213, no. 4, PMC4821646, pp. 621 - 641. DOI: 10.1084/jem.20151182

Deliyanti, D, Lee, JY, Petratos, S, Meyer, CJ, Ward, K, Wilkinson-Berka, J & De Haan-Klein, JB 2016, 'A potent Nrf2 activator, dh404, bolsters antioxidant capacity in glial cells and attenuates ischaemic retinopathy' Clinical Science, vol 130, no. 15, pp. 1375-1387. DOI: 10.1042/CS20160068

Duan, M, Steinfort, DP, Smallwood, D, Hew, M, Chen, W, Ernst, M, Irving, LB, Anderson, GP & Hibbs, ML 2016, 'CD11b immunophenotyping identifies inflammatory profiles in the mouse and human lungs' Mucosal Immunology, vol 9, no. 2, pp. 550-563. DOI: 10.1038/mi.2015.84

Elsworth, B, Sanders, PR, Nebl, T, Batinovic, S, Kalanon, M, Nie, CQ, Charnaud, SC, Bullen, HE, de Koning Ward, TF, Tilley, L, Crabb, BS & Gilson, PR 2016, 'Proteomic analysis reveals novel proteins associated with the Plasmodium protein exporter PTEX and a loss of complex stability upon truncation of the core PTEX component, PTEX150' Cellular Microbiology, vol E-pub, pp. 1551-1569. DOI: 10.1111/cmi.12596

Evans, SM, Earnest, A, Bower, W, Senthuren, M, McLaughlin, P & Stirling, R 2016, 'Timeliness of lung cancer care in Victoria: a retrospective cohort study' Medical Journal of Australia, vol 204, no. 2, pp. 75. DOI: 10.5694/mja15.01026

GEM (Grupo Español de MM)/PETHEMA (Programa para el Estudio de la Terapéutica en Hemopatías Malignas) cooperative study groups 2016, 'Differentiation stage of myeloma plasma cells: Biological and clinical significance' Leukemia. DOI: 10.1038/leu.2016.211

Gervin, K, Page, CM, Aass, HCD, Jansen, MA, Fjeldstad, HE, Andreassen, BK, Duijts, L, van Meurs, JB, van Zelm, MC, Jaddoe, VW, Nordeng, H, Knudsen, GP, Magnus, P, Nystad, W, Staff, AC, Felix, JF & Lyle, R 2016, 'Cell type specific DNA methylation in cord blood: A 450K-reference data set and cell count-based validation of estimated cell type composition' Epigenetics, vol 11, no. 9, pp. 690-698. DOI: 10.1080/15592294.2016.1214782

Jansen, MAE, van den Heuvel, D, Bouthoorn, SH, Jaddoe, VWV, Hooijkaas, H, Raat, H, Fraaij, PLA, van Zelm, MC & Moll, HA 2016, 'Determinants of ethnic differences in cytomegalovirus, Epstein-Barr Virus, and herpes simplex virus type 1 Seroprevalence in childhood' Journal of Pediatrics, vol 170, pp. 126-134e6. DOI: 10.1016/j.jpeds.2015.11.014

Jansen, MAE, van den Heuvel, D, van der Zwet, KVM, Jaddoe, VWV, Hofman, A, Escher, JC, Fraaij, PLA, Hooijkaas, H, van Zelm, MC & Moll, HA 2016, 'Herpesvirus infections and transglutaminase type 2 antibody positivity in childhood: The Generation R Study' Journal of Pediatric Gastroenterology and Nutrition, vol 63, no. 4, pp. 423-430. DOI: 10.1097/MPG.0000000000001163

Jha, JC, Thallas-Bonke, V, Banal, C, Gray, SP, Chow, BSM, Ramm, G, Quaggin, SE, Cooper, ME, Schmidt, HHHW & Jandeleit-Dahm, KA 2016, 'Podocyte-specific Nox4 deletion affords renoprotection in a mouse model of diabetic nephropathy' Diabetologia, vol 59, no. 2, pp. 379-389. DOI: 10.1007/s00125-015-3796-0

Jones, EL, Wee, JL, Demaria, MC, Blakeley, J, Ho, PK, Vega-Ramos, J, Villadangos, JA, Van Spriel, AB, Hickey, MJ, Hammerling, GJ & Wright, MD 2016, 'Dendritic cell migration and antigen presentation are coordinated by the opposing functions of the tetraspanins CD82 and CD37' Journal of Immunology, vol 196, no. 3, pp. 978-987. DOI: 10.4049/jimmunol.1500357

Kristensen, AB, Lay, WN, Ana-Sosa-Batiz, F, Vanderven, HA, Madhavi, V, Laurie, KL, Carolan, L, Wines, BD, Hogarth, M, Wheatley, AK & Kent, SJ 2016, 'Antibody responses with Fc-mediated functions after vaccination of HIV-infected subjects with trivalent influenza vaccine' Journal of Virology, vol 90, no. 12, pp. 5724-5734. DOI: 10.1128/JVI.00285-16

Lalaoui, N, Hanggi, K, Brumatti, G, Chau, D, Nguyen, N-YN, Vasilikos, L, Spilgies, LM, Heckmann, DA, Ma, C, Ghisi, M, Salmon, JM, Matthews, GM, de Valle, E, Moujalled, DM, Menon, MB, Spall, SK, Glaser, SP, Richmond, J, Lock, RB, Condon, SM, Gugasyan, R, Gaestel, M, Guthridge, M, Johnstone, RW, Munoz, L, Wei, A, Ekert, PG, Vaux, DL, Wong, WW-L & Silke, J 2016, 'Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics' Cancer Cell, vol 29, no. 2, pp. 145 - 158. DOI: 10.1016/j.ccell.2016.01.006

Lee, MKS, Moore, X-L, Fu, Y, Al-Sharea, A, Dragoljevic, D, Fernandez-Rojo, MA, Parton, R, Sviridov, D, Murphy, AJ & Chin-Dusting, JPF 2016, 'High-density lipoprotein inhibits human M1 macrophage polarization through redistribution of caveolin-1' British Journal of Pharmacology, vol 173, no. 4, pp. 741-751. DOI: 10.1111/bph.13319

Messina, N, Fulford, T, O'Reilly, L, Loh, WX, Motyer, JM, Ellis, D, McLean, C, Naeem, H, Lin, A, Gugasyan, R, Slattery, RM, Grumont, RJ & Gerondakis, S 2016, 'The NF-¿B transcription factor RelA is required for the tolerogenic function of Foxp3+ regulatory T cells' Journal of Autoimmunity, vol 70, pp. 52-62. DOI: 10.1016/j.jaut.2016.03.017

Murphy, AJ, Kraakman, MJ, Kammoun, HL, Dragoljevic, D, Lee, MKS, Lawlor, KE, Wentworth, JM, Vasanthakumar, A, Gerlic, M, Whitehead, LW, DiRago, L, Cengia, L, Lane, RM, Metcalf, D, Vince, JE, Harrison, LC, Kallies, A, Kile, BT, Croker, BA, Febbraio, MA & Masters, SL 2016, 'IL-18 production from the NLRP1 inflammasome prevents obesity and metabolic syndrome' Cell Metabolism, vol 23, no. 1, pp. 155-164. DOI: 10.1016/j.cmet.2015.09.024

Nievergall, E, Reynolds, J, Kok, CH, Watkins, DB, Biondo, M, Busfield, SJ, Vairo, G, Fuller, K, Erber, WN, Sadras, T, Grose, R, Yeung, DT, Lopez, AF, Hiwase, DK, Hughes, TP & White, DL 2016, 'TGF-[alpha] and IL-6 plasma levels selectively identify CML patients who fail to achieve an early molecular response or progress in the first year of therapy' Leukemia, vol 30, no. 6, pp. 1263-1272. DOI: 10.1038/leu.2016.34

Noho-Konteh, F, Adetifa, JU, Cox, M, Hossin, S, Reynolds, J, Le, MT, Sanyang, LC, Drammeh, A, Plebanski, M, Forster, T, Dickinson, P, Ghazal, P, Whittle, H, Rowland-Jones, SL, Sutherland, JS & Flanagan, KL 2016, 'Sex-differential non-vaccine-specific immunological effects of diphtheria-tetanus-pertussis and measles vaccination' Clinical Infectious Diseases, vol 63, no. 9, pp. 1213-1226. DOI: 10.1093/cid/ciw492

Perret, JL, Walters, H, Johns, D, Gurrin, L, Burgess, J, Lowe, A, Thompson, B, Markos, J, Morrison, S, Thomas, P, Mcdonald, C, Wood-Baker, R, Hopper, J, Svanes, C, Giles, G, Abramson, M, Matheson, M & Dharmage, S 2016, 'Mother's smoking and complex lung function of offspring in middle age: A cohort study from childhood' Respirology, vol 21, pp. 911-919. DOI: 10.1111/resp.12750

Pizzolla, A, Oh, DY, Luong, S, Prickett, SR, Henstridge, DC, Febbraio, MA, O'Hehir, RE, Rolland, JM & Hardy, CL 2016, 'High fat diet inhibits dendritic cell and T cell response to allergens but does not impair inhalational respiratory tolerance' PLoS ONE, vol 11, no. 8, e0160407. DOI: 10.1371/journal.pone.0160407

Radhakrishna, N, Prickett, S, Phan, T, Rolland, JM, Puy, R & O'Hehir, RE 2016, 'Anaphylaxis to oats after cutaneous sensitization by oatmeal in skin products used for the treatment of atopic dermatitis' The Journal of Allergy and Clinical Immunology: In Practice, vol 4, no. 1, pp. 152-153. DOI: 10.1016/j.jaip.2015.07.005

Rother, MB, Jensen, K, van der Burg, M, van de Bovenkamp, FS, Kroek, R, van Ijcken, WFJ, van der Velden, VHJ, Cupedo, T, Olstad, OK, van Dongen, JJM & Van Zelm, MC 2016, 'Decreased IL7Ra and TdT expression underlie the skewed immunoglobulin repertoire of human B-cell precursors from fetal origin' Scientific Reports, vol 6, 33924. DOI: 10.1038/srep33924

Rother, MB, Schreurs, MWJ, Kroek, R, Bartol, SJW, Van Dongen, JJM & Van Zelm, MC 2016, 'The human thymus is enriched for autoreactive B cells' Journal of Immunology, vol 197, no. 2, pp. 441-448. DOI: 10.4049/jimmunol.1501992

Sato, T, Paquet-Fifield, S, Harris, NC, Roufail, S, Turner, DJ, Yuan, Y, Zhang, YF, Fox, SB, Hibbs, ML, Wilkinson-Berka, JL, Williams, RA, Stacker, SA, Sly, PD & Achen, MG 2016, 'VEGF-D promotes pulmonary oedema in hyperoxic acute lung injury' Journal of Pathology, vol 239, no. 2, pp. 152-161. DOI: 10.1002/path.4708

Saulep-Easton, D, Vincent, FB, Quah, PS, Wei, A, Ting, SB, Croce, CM, Tam, C & Mackay, F 2016, 'The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells' Leukemia, vol 30, no. 1, pp. 163 - 172. DOI: 10.1038/leu.2015.174

Sullivan, LC, Berry, R, Sosnin, N, Widjaja, JML, Deuss, FA, Balaji, GR, Trapani, JA, LaGruta, NL, Mirams, M, Trapani, JA, Rossjohn, J, Brooks, AG & Andrews, DM 2016, 'Recognition of the major histocompatibility complex (MHC) class Ib molecule H2-Q10 by the natural killer cell receptor Ly49C' Journal of Biological Chemistry, vol 291, no. 36, pp. 18740-18752. DOI: 10.1074/jbc.M116.737130

Talia, DM, Deliyanti, D, Agrotis, A & Wilkinson-Berka, JL 2016, 'Inhibition of the nuclear receptor ROR¿ and interleukin-17A suppresses neovascular retinopathy' Arteriosclerosis Thrombosis and Vascular Biology, vol 36, no. 6, pp. 1186-1196. DOI: 10.1161/ATVBAHA.115.307080

Tay, TR, Bosco, J, Gillman, A, Aumann, H, Stirling, R, O'Hehir, R & Hew, M 2016, 'Coexisting atopic conditions influence the likelihood of allergic bronchopulmonary aspergillosis in asthma' Annals of Allergy Asthma & Immunology, vol 117, no. 1, e1, pp. 29 - 32. DOI: 10.1016/j.anai.2016.04.024

Tay, TR, Lee, J, Radhakrishna, N, Hore-Lacy, F, Stirling, R, Hoy, R, Dabscheck, E, O'Hehir, R & Hew, M 2016, 'A Structured Approach to Specialist-referred Difficult Asthma Patients Improves Control of Comorbidities and Enhances Asthma Outcomes' The Journal of Allergy and Clinical Immunology: In Practice. DOI: 10.1016/j.jaip.2016.12.030

Thurgood, J, Dubsky, S, Uesugi, K, Curtis, M, Samarage, CR, Thompson, B, Zosky, G & Fouras, A 2016, 'Imaging lung tissue oscillations using high-speed X-ray velocimetry' Journal of Synchrotron Radiation, vol 23, no. Part 1, pp. 324-330. DOI: 10.1107/S1600577515021700

Timmermans, WMC, van Laar, JAM, van der Houwen, TB, Kamphuis, LSJ, Bartol, SJW, Lam, KH, Ouwendijk, RJ, Sparrow, MP, Gibson, PR, van Hagen, PM & van Zelm, MC 2016, 'B-cell dysregulation in Crohn's disease is partially restored with infliximab therapy' PLoS ONE, vol 11, no. 7, e0160103. DOI: 10.1371/journal.pone.0160103

van der Heiden, M, Van Zelm, MC, Bartol, SJW, de Rond, LGH, Berbers, GAM, Boots, AMH & Buisman, AM 2016, 'Differential effects of cytomegalovirus carriage on the immune phenotype of middle-aged males and females' Scientific Reports, vol 6, 26892, pp. 1-12. DOI: 10.1038/srep26892

Wang, B, Yao, K, Huuskes, BM, Shen, H-H, Zhuang, J, Godson, C, Brennan, EP, Wilkinson-Berka, JL, Wise, AF & Ricardo, SD 2016, 'Mesenchymal stem cells deliver exogenous microRNA-let7c via exosomes to attenuate renal fibrosis' Molecular Therapy, vol 24, no. 7, pp. 1290-1301. DOI: 10.1038/mt.2016.90

Wang, X, Gkanatsas, Y, Palasubramaniam, J, Hohmann, JD, Chen, YC, Lim, B, Hagemeyer, CE & Peter, K 2016, 'Thrombus-targeted theranostic microbubbles: A new technology towards concurrent rapid ultrasound diagnosis and bleeding-free fibrinolytic treatment of thrombosis' Theranostics, vol 6, no. 5, pp. 726 - 738. DOI: 10.7150/thno.14514

Wijeysundera, DN, Pearse, RM, Shulman, MA, Abbott, TEF, Torres, E, Croal, BL, Granton, JT, Thorpe, KE, Grocott, MPW, Farrington, C, Myles, PS, Cuthbertson, BH & METS Study Investigators 2016, 'Measurement of Exercise Tolerance before Surgery (METS) study: A protocol for an international multicentre prospective cohort study of cardiopulmonary exercise testing prior to major non-cardiac surgery' BMJ Open, vol 6, no. 3, e010359. DOI: 10.1136/bmjopen-2015-010359

Wilson, KL, Xiang, SD & Plebanski, M 2016, 'A model to study the impact of polymorphism driven liver-stage immune evasion by malaria parasites, to help design effective cross-reactive vaccines' Frontiers in Microbiology, vol 7, no. MAR, 303. DOI: 10.3389/fmicb.2016.00303

Wines, BD, Vanderven, HA, Esparon, SE, Kristensen, AB, Kent, SJ & Hogarth, PM 2016, 'Dimeric FcgR ectodomains as probes of the Fc receptor function of anti-influenza virus IgG' Journal of Immunology, vol 197, no. 4, pp. 1507-1516. DOI: 10.4049/jimmunol.1502551