Powell group

Molecular epilepsy research group

Key terms

Molecular epilepsy, cardiac function, ion channels

2018 Powell group. L-R: Mr Michael Li, Dr Kim Powell, Mr Marcus Choi, Ms Emma Braine, Dr Pablo Espinosa

Our research centers on basic research investigating the causal mechanisms of cardiac dysfunction and sudden unexpected death in epilepsy (SUDEP) in epilepsy. We study how alternations in function or expression of ion channels and mRNA and protein levels in both brain and heart tissue result in cardiac dysfunction in people with epilepsy. We compare our findings with animal models and clinical information to get a complete picture to inform strategies for prevention and treatment.