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Phospholipids – fat molecules that form the membranes found around cells – are highly abundant, but when it comes to autoimmune diseases, their role has largely been overlooked. Recent research has pointed to a role for lipids in numerous diseases, including psoriasis, contact hypersensitivities and allergies. The development of autoimmune diseases such as these is now better understood thanks to researchers from the Australian Research Council Centre of Excellence in Advanced Molecular Imaging (Imaging CoE) and Brigham and Women’s Hospital at Harvard Medical School in the USA.