MHTP success in latest NHMRC funding announcement

The MHTP Precinct has received over $35 million to lead 22 research projects in the latest National Health and Medical Research Council (NHMRC) funding announcement.

The Federal Minister for Health, the Hon. Greg Hunt MP, made the announcement on December 7 and said the funding would support more than 400 research projects worth over $400 million.

Medical researchers at Monash University were awarded more than $76 million in funding from the NHMRC, placing Monash above any other Australian University.

Of the $35.5 million awarded to MHTP, $21.5 million will fund projects in the School of Clinical Sciences (SCS), including four Ideas Grants, seven Investigator Grants, and two CTCS Grants.

Professor Michael Hickey, Director of the Centre for Inflammatory Diseases, received an $805,360 Ideas Grant to research how regulatory T cells work to ‘switch off’ inflammation and protect organs from damage. Dr Connie Wong, also from the Centre for Inflammatory Diseases, received almost $900,000 for her research to identify the signalling pathways that underlie gut barrier breakdown after stroke, and also assess the potential of a novel pharmacological approach for reducing bacterial infection in stroke patients.

Professor Yahya Shehabi, Program Director of Critical Care in SCS, was awarded a CTCS Grant worth almost $5 million for his SPICE IV trial. The trial will focus on whether the use of dexmedetomidine as a primary sedative in older ICU patients reduces long-term mortality and delirium. This follows on from Professor Shehabi’s SPICE III trial in which a large scale trial of dexmedetomidine revealed a survival benefit in a subgroup of patients over 65 years of age.

The success of SCS researchers highlights the strength of collaborative research across the MHTP precinct. Congratulations to all our 2019 NHMRC grant recipients;

Professor Michael Hickey
Control of Proinflammatory Endothelial Cell function by Regulatory T cells
Ideas Grant
Dr Connie Wong
Targeting the brain-gut axis to improve stroke outcome
Ideas Grant
Professor Kate Loveland
Developmental Events Affecting Male Fertility and Reproductive Pathologies
Ideas Grant
Dr Jun Yang
Screening for Primary Aldosteronism: Outcomes, Economics and Biomarkers
Ideas Grant
Dr Michelle Tate
Finding the balance – Reducing inflammation during severe influenza infections
Ideas Grant
Dr Sam Forster
Microbiome derived candidates to revolutionise treatment of inflammatory bowel disease
Ideas Grant
Dr Shayanti Mukherjee
Advancing Women’s Urogynecological Health using Micro/Nanotechnologies
Ideas Grant
Professor Mark Hedger
Treating Inflammation in the Male Reproductive Tract
Ideas Grant
Dr Kelly Crossley
Reducing the risk of pulmonary hypertension in infants with a congenital diaphragmatic hernia
Ideas Grant
Professor Guiying Nie
The central role of accelerated trophoblast syncytialization and aging in preeclampsia
Ideas Grant
Dr Kate Lawlor
Role of A1 in repressing mitochondrial apoptosis to limit pathogen clearance
Ideas Grant
Dr Beth Allison
Improved cardiovascular outcomes for growth-restricted infants
Investigator Grant (EL1)
Professor Ben Mol
Towards sustainable evidence-based pathways in perinatology and reproductive medicine: evidence synthesis in women's health on a global scale.
Investigator Grant (L3)
Dr David Scott
Optimising Exercise Interventions for Maintaining Physical Function, Bone and Muscle Health in Older Adults with Obesity and Osteoarthritis
Investigator Grant (EL2)
Professor Caroline Gargett
Translating Endometrial Stem/Progenitor Cell Discoveries to Transform Women's and Girls' Gynaecological Health Outcomes
Investigator Grant (L1)
Dr Calum Roberts
Life in Transition: Optimising Early Respiratory Support in the Preterm Infant
Investigator Grant (EL1)
Professor Elizabeth Hartland
Towards precision microbiology: new strategies to combat bacterial infection
Investigator Grant (L2)
Assoc. Prof Graeme Polglase
Reducing the consequences of prematurity by improving the transition at birth
Investigator Grant (L1)
Assoc. Prof Claudia Nold
Interventional Immunology in Early Life Diseases
Investigator Grant (L1)
Dr Kirsten Palmer
PROTECT Me: Assessing Antenatal Maternal Melatonin Supplementation in Fetal Growth Restriction to Improve Neurodevelopmental Outcomes
Clinical Trials and Cohort Studies (CTCS) Grant
Professor Yahya Shehabi
Sedation Practice in Intensive Care Evaluation in Older ventilated Critically Ill patients; Early Sedation with Dexmedetomidine in Older Ventilated Critically Ill Patients. A Randomised Double Blind Placebo Controlled Trial - SPICE IV
Clinical Trials and Cohort Studies (CTCS) Grants
Professor Paul Hertzog
Innate Mucosal Sensing & Shaping of the Human-Microbiome
Synergy Grant