Can Aspirin improve venous leg ulcer healing?

Aspirin is a widely used drug that has several actions potentially capable of influencing the progression of VLUs.

Animal studies suggest that aspirin can suppress inflammation and promote ulcer healing.

Data from two small clinical studies from the UK and Spain suggest that aspirin (300mg daily) may speed healing rates and possibly prevent VLU recurrence.

However, robust evidence for effectiveness of aspirin from high-quality, randomised controlled trials is lacking.