Inflammatory Respiratory Disease Research Group

About the Inflammatory Respiratory Disease Research Group

Chronic Obstructive Lung Disease (COPD) is the fourth major killer worldwide. Smoking and pollution are major factors. Smoking damaged lungs are susceptible to chronic bacterial invasion and inflammation leading to loss of lung and formation of scars (emphysema and bronchitis).  We have shown Haemophilus is the major bacterial pathogen in COPD and that sufferers have abnormal and inefficient immune responses. Defining the molecular basis of these defective immune responses has provided opportunities to enhance immunity and reduce the injurious inflammation.

The outcome in respiratory infection is primarily determined by the interaction between the bacterial pathogen and host immune response. We have a longstanding research interest in assessing the immune response to common bacteria. Our work has concentrated on clinical samples from patients and cell lines.

Group head

Dr Paul King

Our staff

roleen-sharmaResearch assistant
Roleen Sharma

Publications

Read and access our key publications.

Opportunities

If you are thinking of a career in biomedical research The School of Clinical Sciences is a great place to start. We are located at Monash Medical Centre (MMC) Clayton within easy walking distance of both Monash University Clayton Campus and the Clayton Shopping District.

Find out more about current postgraduate opportunities (Honours, Masters, PhD).