Blood DNA methylation as a potential biomarker of dementia: A systematic review. Fransquet PD, Lacaze P, Saffery R, McNeil J, Woods R & Ryan J. Jan 2018 In : Alzheimer's and Dementia. 14, 1, p. 81-103 18p.
Cohort profile: The Triple B Pregnancy Cohort Study: A longitudinal study of the relationship between alcohol, tobacco and other substance use during pregnancy and the health and well-being of Australian children and families. Hutchinson D, Wilson J, Allsop S, Elliott E, Najman J, Burns L, Bartu A, Jacobs S, Honan I, McCormack C, Rossen L, Fiedler H, Stone C, Khor S, Ryan J, Youssef GJ, Olsson CA, Mattick RP & The Triple B Research Consortium 1 Feb 2018 In : International Journal of Epidemiology. 47, 1, p. 26-27m 15 p., dyx218.
DNA methylation and genetic variation of the angiotensin converting enzyme (ACE) in depression. Lam D, Ancelin ML, Ritchie K, Saffery R & Ryan J. 1 Feb 2018 In : Psychoneuroendocrinology. 88, p. 1-8 8 p.
Effect of Aspirin on All-Cause Mortality in the Healthy Elderly. McNeil JJ, Nelson MR, Woods RL, Lockery JE, Wolfe R, Reid CM, Kirpach BR, Shah RC, Ives DG, Storey E, Ryan J, Tonkin AM, Newman AB, Williamson JD, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Orchard SG & 9 others. 16 Sep 2018 (Accepted/In press) In : New England Journal of Medicine. 10 p.
Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly. McNeil JJ, Wolfe R, Woods RL, Tonkin AM, Donnan GA, Nelson MR, Reid CM, Lockery JE, Kirpach BR, Storey E, Shah RC, Williamson JD, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Orchard SG, Trevaks RE, Beilin LJ & 14 others. 16 Sep 2018 (Accepted/In press) In : New England Journal of Medicine. 10 p.
Effect of Aspirin on Disability-free Survival in the Healthy Elderly. McNeil JJ, Woods RL, Nelson MR, Reid CM, Kirpach BR, Wolfe R, Storey E, Shah RC, Lockery JE, Tonkin AM, Newman AB, Williamson JD, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Ives DG, Fitzgerald SM, Orchard SG, Trevaks RE & 9 others. 16 Sep 2018 (Accepted/In press) In : New England Journal of Medicine. 10 p.
Epigenetics: a missing link in understanding psychiatric disorders? Ryan J, Saffery R & Patton G. 1 Jan 2018 In : The Lancet Psychiatry. 5, 1, p. 65-78 14 p.
Maternal depression, antidepressant use and placental oxytocin receptor DNA methylation: Findings from the MPEWS study. Galbally M, Ryan J, van IJzendoorn M, Watson SJ, Spigset O, Lappas M, Saffery R, de Kloet R & Lewis AJ. 1 Apr 2018 In : Psychoneuroendocrinology. 90, p. 1-8 8 p.
Mental health trajectories among women in Australia as they age. Tran T, Hammarberg K, Ryan J, Lowthian J, Freak-Poli R, Owen A, Kirkman M, Curtis A, Rowe H, Brown H, Ward S, Britt C & Fisher J. 1 May 2018 (Accepted/In press) In : Aging and Mental Health. p. 1-10 10 p.
Micro RNA as a potential blood-based epigenetic biomarker for Alzheimer's disease. Fransquet PD & Ryan J. 1 Aug 2018 In : Clinical Biochemistry. 58, p. 5-14 10 p.
Normative performance of healthy older individuals on the Modified Mini-Mental State (3MS) examination according to ethno-racial group, gender, age, and education level. Ryan J, Woods RL, Britt C, Murray AM, Shah RC, Reid CM, Kirpach B, Wolfe RS, Nelson MR, Lockery JE, Orchard SG, Trevaks RE, McNeil JJ, Storey E & on behalf of the ASPREE Investigator Group. 6 Jul 2018 (Accepted/In press) In : Clinical Neuropsychologist. p. 1-19 19 p.
Phenotypic Heterogeneity in Dementia: A Challenge for Epidemiology and Biomarker Studies. Ryan J, Fransquet P, Wrigglesworth J & Lacaze P. 19 Jun 2018 In : Frontiers in Public Health. 2018, 6 p., 00181
The role of oxytocin receptor gene (OXTR) DNA methylation (DNAm) in human social and emotional functioning: A systematic narrative review. Maud C, Ryan J, McIntosh JE & Olsson CA. 29 May 2018 In : BMC Psychiatry. 18, 1, 13 p., 154.
Time- and sex-dependent associations between prenatal alcohol exposure and placental global DNA methylation. Loke YJ, Muggli E, Nguyen L, Ryan J, Saffery R, Elliott EJ, Halliday J & Craig JM. 1 Jul 2018 In : Epigenomics. 10, 7, p. 981-991 11 p.
5-HTTLPR × stress hypothesis: is the debate over? Ancelin M-L & Ryan JL. 17 Sep 2017 In : Molecular Psychiatry. 2 p.
Cannabis use by women during pregnancy does not influence infant DNA methylation of the dopamine receptor DRD4. Fransquet PD, Hutchinson DM, Olsson CA, Allsop S, Elliott EJ, Burns L, Mattick R, Saffery R & Ryan J. 2017 In : American Journal of Drug and Alcohol Abuse. 43, 6, p. 671-677 7 p.
Chronic and remitting trajectories of depressive symptoms in the elderly. Characterisation and risk factors. Carrière I, Farré A, Proust-Lima C, Ryan J, Ancelin ML & Ritchie K. Apr 2017 In : Epidemiology and Psychiatric Sciences. 26, 2, p. 146 - 156 11 p.
Does maternal mental well-being in pregnancy impact the early human epigenome? Ryan J, Mansell T, Fransquet P & Saffery R. 1 Mar 2017 In : Epigenomics. 9, 3, p. 313-322 10 p.
Genetic association of rs1344706 in ZNF804A with bipolar disorder and schizophrenia susceptibility in Chinese populations. Rao S, Yao Y, Ryan J, Jin C, Xu Y, Huang X, Guo J, Wen Y, Mao C, Meyre D & Zhang F. 25 Jan 2017 In : Scientific Reports. 7, 8 p., 41140.
Heterogeneity in HPA axis dysregulation and serotonergic vulnerability to depression. Ancelin M-L, Scali J, Norton J, Ritchie K, Dupuy A-M, Chaudieu I & Ryan J. 1 Mar 2017 In : Psychoneuroendocrinology. 77, p. 90-94 5 p.
Hormone treatment. Ryan J. 2017 The SAGE Encyclopedia of Abnormal and Clinical Psychology. Wenzel, A. (ed.). Thousand Oaks CA USA: SAGE Publications Ltd, p. 1696-1697 2 p.
Investigating direct links between depression, emotional control, and physical punishment with adolescent drive for thinness and bulimic behaviors, including possible moderation by the serotonin transporter 5-HTTLPR polymorphism. Rozenblat V, Ryan J, Wertheim EH, King R, Olsson CA & Krug I. 9 Aug 2017 In : Frontiers in Psychology. 8, AUG, 1361.
Investigating the epigenetic profile of the inflammatory gene IL-6 in late-life depression. Ryan J, Pilkington L, Neuhaus K, Ritchie K, Ancelin ML & Saffery R. 25 Oct 2017 In : BMC Psychiatry. 17, 1, 354.
Mercy Pregnancy and Emotional Well-being Study (MPEWS): Understanding maternal mental health, fetal programming and child development. Study design and cohort profile. Galbally M, van IJzendoorn M, Permezel M, Saffery R, Lappas M, Ryan J, Van Rossum E, Johnson AR, Teti D & Lewis AJ. 1 Dec 2017 In : International Journal of Methods in Psychiatric Research. 26, 4, 10 p., e1558.
Pathogenic variants in the healthy elderly: Unique ethical and practical challenges. Lacaze P, Ryan J, Woods R, Winship I & McNeil J. Oct 2017 In : Journal of Medical Ethics. 43, 10, p. 714-722 9 p., 103967.
Preliminary evidence for a role of the adrenergic nervous system in generalized anxiety disorder. Zhang X, Norton J, Carrière I, Ritchie K, Chaudieu I, Ryan J & Ancelin M-L. 15 Feb 2017 In : Scientific Reports. 7, 9 p., 42676.
Relationships Between Self-Reported and Observed Parenting Behaviour, Adolescent Disordered Eating Attitudes and Behaviours, and the 5-HTTLPR Polymorphism: Data From the Australian Temperament Project. Rozenblat V, Ryan J, Wertheim E, King R, Olsson CA, Letcher P & Krug I. 1 Sep 2017 In : European Eating Disorders Review. 25, 5, p. 381-388 8 p.
The Dangers of Direct-to-Consumer Genetic Testing for Alzheimer’s Disease: Comment on “Personal Genomic Testing, Genetic Inheritance, and Uncertainty”. Lacaze P, Tiller J & Ryan J. Dec 2017 In : Journal of Bioethical Inquiry. 14, 4, p. 585-587 3 p.
The effect of an adverse psychological environment on salivary cortisol levels in the elderly differs by 5-HTTLPR genotype. Ancelin ML, Scali J, Norton J, Ritchie K, Dupuy AM, Chaudieu I & Ryan J. 1 Dec 2017 In : Neurobiology of Stress. 7, p. 38-46 9 p.
The impact of psychological distress during pregnancy on the developing fetus: Biological mechanisms and the potential benefits of mindfulness interventions. Isgut M, Smith AK, Reimann ES, Kucuk O & Ryan J. 20 Dec 2017 In : Journal of Perinatal Medicine. 45, 9, p. 999-1011 13 p.
Biological underpinnings of trauma and post-traumatic stress disorder: Focusing on genetics and epigenetics. Ryan J, Chaudieu I, Ancelin M-L & Saffery R. 1 Nov 2016 In : Epigenomics. 8, 11, p. 1553-1569 17 p.
Common variants in CACNA1C and MDD susceptibility: A comprehensive meta-analysis. Rao S, Yao Y, Zheng C, Ryan J, Mao C, Zhang F, Meyre D & Xu Q. 1 Sep 2016 In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 171, 6, p. 896-903 8 p.
Common variants in FKBP5 gene and major depressive disorder (MDD) susceptibility: A comprehensive meta-analysis. Rao S, Yao Y, Ryan J, Li T, Zheng C, Xu Y & Xu Q. 7 Sep 2016 In : Scientific Reports. 6, 7 p., 32687.
GWAS-identified risk variants for major depressive disorder: Preliminary support for an association with late-life depressive symptoms and brain structural alterations. Ryan J, Artero S, Carriere I, Maller JJ, Reglade-Meslin C, Ritchie KA & Ancelin M-L. 2016 In : European Neuropsychopharmacology. 26, 1, p. 113-125 9 p.
Maternal mental well-being during pregnancy and glucocorticoid receptor gene promoter methylation in the neonate. Barwon Infant Study Investigator Team & Ryan J. 1 Nov 2016 In : Development and Psychopathology. 28, 4, p. 1421-1430 10 p.
Meta-analysis indicates that SNP rs9939609 within FTO is not associated with major depressive disorder (MDD) in Asian population. Yao Y, Wen Y, Du T, Sun N, Deng H, Ryan J & Rao S. 2016 In : Journal of Affective Disorders. 193, p. 27-30 4 p.
Perinatal maternal alcohol consumption and methylation of the dopamine receptor DRD4 in the offspring: the Triple B study. Fransquet PD, Hutchinson D, Olsson CA, Wilson J, Allsop S, Najman J, Elliott E, Mattick RP, Saffery R, Ryan J & The Triple B Research Consortium 7 Dec 2016 In : Environmental Epigenetics. 2, 4, 9 p., dvw023.
Preliminary indications of the effect of a brief yoga intervention on markers of inflammation and DNA methylation in chronically stressed women. Harkess K, Ryan J, Delfabbro PH & Cohen-Woods S. 1 Nov 2016 In : Translational Psychiatry. 6, 11, 9 p., e965.
The effects of maternal anxiety during pregnancy on IGF2/H19 methylation in cord blood. Mansell T, Novakovic B, Meyer B, Rzehak P, Vuillermin P, Ponsonby A-L, Collier F, Burgner D, Saffery R, Ryan J & BIS investigator team. 2016 In : Translational Psychiatry. 6, 3, e765.
BDNF promoter methylation and genetic variation in late-life depression. Januar V, Ancelin ML, Ritchie K, Saffery R & Ryan J. 25 Aug 2015 In : Translational Psychiatry. 5, 8, 7 p., e619.
C-reactive protein gene variants: Independent association with late-life depression and circulating protein levels. Ancelin ML, Farré A, Carriere I, Ritchie K, Chaudieu I & Ryan J. 20 Jan 2015 In : Translational Psychiatry. 5, 1, 8 p., e499.
Epigenetics and depressive disorders: A review of current progress and future directions. Januar V, Saffery R & Ryan J. 1 Aug 2015 In : International Journal of Epidemiology. 44, 4, p. 1364-1387 24 p.
Involvement of GPR50 polymorphisms in depression: Independent replication in a prospective elderly cohort. Ryan J, Carrière I, Ritchie K & Ancelin M-L. 1 Mar 2015 In : Brain and Behavior. 5, 3, p. e00313 10 p., e00313.
Brain volumes in late life: Gender, hormone treatment, and estrogen receptor variants. Ryan JL, Artero S, Carriere I, Scali J, Maller JJ, Meslin C, Ritchie KA, Scarabin PY & Ancelin M-L. 2014 In : Neurobiology of Aging. 35, 3, p. 645 - 654 10 p.
Crucial timing in schizophrenia: role of DNA methylation in early neurodevelopment. Ryan J & Saffery R. Oct 2014 In : Genome Biology. 15, 10, 4 p., 495.
Estrogen receptor polymorphisms and incident dementia: The prospective 3C study. Ryan J, Carrière I, Carcaillon L, Dartigues J-F, Auriacombe S, Rouaud O, Berr C, Ritchie K, Scarabin PY & Ancelin ML. Jan 2014 In : Alzheimer's and Dementia. 10, 1, p. 27-35 9 p.
Impact of a premature menopause on cognitive function in later life. Ryan J, Scali J, Carriere I, Amieva H, Rouaud O, Berr C, Ritchie K & Ancelin M-L. 1 Dec 2014 In : BJOG: an International Journal of Obstetrics and Gynaecology. 121, 13, p. 1729-1739 11 p.
Postnatal stability, tissue, and time specific effects of AHRR methylation change in response to maternal smoking in pregnancy. Novakovic B, Ryan J, Pereira N, Boughton B, Craig JM & Saffery R. Mar 2014 In : Epigenetics. 9, 3, p. 377-386 10 p.
Angiotensin-converting enzyme gene variants are associated with both cortisol secretion and late-life depression. Ancelin M-L, Carriere I, Scali J, Ritchie K, Chaudieu I & Ryan J. 19 Nov 2013 In : Translational Psychiatry. 3, 7 p., e322.
Anxiety and mortality risk in community-dwelling elderly people. Carriere I, Ryan J, Norton J, Scali J, Stewart R, Ritchie K & Ancelin M-L. Oct 2013 In : British Journal of Psychiatry. 203, 4, p. 303-309 7 p.
Genetic status of estrogen receptor modifies the relation of postmenopausal hormone therapy with carotid atherosclerosis among older postmenopausal women. The Three-City Cohort study. Canonico M, Giroud M, Ryan J, Helmer C & Scarabin P-Y. 26 Nov 2013 p. 12978 1 p.
Lifelong estrogen exposure and memory in older postmenopausal women. Tierney MC, Ryan J, Ancelin ML, Moineddin R, Rankin S, Yao C & Maclusky NJ. 2013 In : Journal of Alzheimer's Disease. 34, 3, p. 601-608 8 p.
Lifetime endogenous reproductive factors and severe depressive symptoms in postmenopausal women: Findings from the E3N cohort. Perquier F, Ryan J, Ancelin M-L, Mesrine S & Clavel-Chapelon F. Nov 2013 In : Menopause. 20, 11, p. 1154-1163 10 p.
Prospective analysis of the association between estrogen receptor gene variants and the risk of cognitive decline in elderly women. Ryan J, Carriere I, Amieva H, Rouaud O, Berr C, Ritchie K, Scarabin PY & Ancelin M-L. Dec 2013 In : European Neuropsychopharmacology. 23, 12, p. 1763-1768 6 p.
The 1,2,4-triazole as a scaffold for the design of ghrelin receptor ligands: Development of JMV 2959, a potent antagonist. Moulin A, Brunel L, Boeglin D, Demange L, Ryan J, M'Kadmi C, Denoyelle S, Martinez J & Fehrentz J-A. Feb 2013 In : Amino Acids. 44, 2, p. 301-314 14 p.
Endogenous oestradiol as a positive correlate of plasma fibrinogen among older postmenopausal women: A population-based study (the Three-City cohort study). Canonico M, Brailly-Tabard S, Gaussem P, Setiao J, Rouaud O, Ryan J, Carcaillon L, Guiochon-Mantel A & Scarabin PY. Dec 2012 In : Clinical Endocrinology. 77, 6, p. 905-910 6 p.
Estrogen receptor alpha gene variants and major depressive episodes. Ryan J, Scali J, Carriere I, Peres K, Rouaud O, Scarabin P-Y, Ritchie K & Ancelin M-L. Feb 2012 In : Journal of Affective Disorders. 136, 3, p. 1222-1226 5 p.
High level of plasma estradiol as a new predictor of ischemic arterial disease in older postmenopausal women: The Three-City Cohort study. Scarabin-Carré V, Canonico M, Brailly-Tabard S, Trabado S, Ducimetière P, Giroud M, Ryan J, Helmer C, Plu-Bureau G, Guiochon-Mantel A & Scarabin P-Y. 8 Jun 2012 In : American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease. 1, 3, 10 p., e001388.
Hormone levels and cognitive function in postmenopausal midlife women. Ryan J, Stanczyk FZ, Dennerstein L, Mack WJ, Clark, MS, Szoeke C, Kildea D & Henderson VW. Mar 2012 In : Neurobiology of Aging. 33, 3, p. 617.e11-617.e22 12 p.
Hormone treatment, estrogen receptor polymorphisms and mortality: A prospective cohort study. Ryan J, Canonico M, Carcaillon L, Carrière I, Scali J, Dartigues J-F, Dufouil C, Ritchie K, Scarabin PY & Ancelin M-L. 23 Mar 2012 In : PLoS ONE. 7, 3, 7 p., e34112.
Low plasma testosterone and elevated carotid intima-media thickness: Importance of low-grade inflammation in elderly men. Soisson, V., Brailly-Tabard, S., Empana, J-P., Féart , C., Ryan, J., Bertrand, M., Guiochon-Mantel, A. & Scarabin, P. Y. Jul 2012 In : Atherosclerosis. 223, 1, p. 244-249 6 p.
Polymorphisms of estrogen receptors and risk of depression: Therapeutic implications. Ryan, J. & Ancelin, M-L. 2012 In : Drugs. 72, 13, p. 1725-1738 14 p.
Estrogen receptor gene variants are associated with anxiety disorders in older women. Ryan, J., Scali, J., Carrière, I., Scarabin, P. Y., Ritchie, K. & Ancelin, M-L. Nov 2011 In : Psychoneuroendocrinology. 36, 10, p. 1582-1586 5 p.
Executive functions in recently postmenopausal women: Absence of strong association with serum gonadal steroids. Ryan, J., Stanczyk, F. Z., Dennerstein, L., Mack, W. J., Clark, M. S., Szoeke, C. & Henderson, V. W. 16 Mar 2011 In : Brain Research. 1379, p. 199-205 7 p.
Oestrogen receptor polymorphisms and late-life depression. Ryan, J., Scali, J., Carrière, I., Peres, K., Rouaud, O., Scarabin, P. Y., Ritchie, K. & Ancelin, M. L. Jul 2011 In : British Journal of Psychiatry. 199, 2, p. 126-131 6 p.
A prospective study of hormone therapy and depression in community-dwelling elderly women: The three city study. Scali, J., Ryan, J., Carrière, I., Dartigues, J. F., Tavernier, B., Ritchie, K. A. & Ancelin, M-L. Dec 2010 In : Journal of Clinical Psychiatry. 71, 12, p. 1673-1679 7 p.
A prospective study of hormonal treatment and anxiety disorders in community-dwelling elderly women (The Esprit Study). Scali, J., Ryan, J., Carrière, I., Ritchie, K. A. & Ancelin, M-L. May 2009 In : Journal of Affective Disorders. 115, 1-2, p. 274-279 6 p.
A prospective study of the association between endogenous hormones and depressive symptoms in postmenopausal women. Ryan, J., Burger, H. G., Szoeke, C., Lehert, P., Ancelin, M-L., Henderson, V. W. & Dennerstein, L. May 2009 In : Menopause. 16, 3, p. 509-517 9 p.
Characteristics of hormone therapy, cognitive function, and dementia: The prospective 3C study. Ryan, J., Carrière, I., Scali, J., Dartigues, J-F., Tzourio, C., Poncet, M., Ritchie, K. & Ancelin, M-L. Nov 2009 In : Neurology. 73, 21, p. 1729-1737 9 p.
Life-time estrogen exposure and cognitive functioning in later life. Ryan, J., Carrière, I., Scali, J., Ritchie, K. A. & Ancelin, M-L. Feb 2009 In : Psychoneuroendocrinology. 34, 2, p. 287-298 12 p.
The Wnt target jagged-1 mediates the activation of notch signaling by progastrin in human colorectal cancer cells
Pannequin, J., Bonnans, C., Delaunay, N., Ryan, J., Bourgaux, J. F., Joubert, D. & Hollande, F. 1 Aug 2009 In : Cancer Research. 69, 15, p. 6065-6073 9 p.