Nodular Hyperplasia of Prostate

Clinical History

A 78 year old man presented to Casualty with an episode of acute retention. After treatment he developed acute myocardial infarction and died.

Pathology

The anterior wall of the bladder has been opened to display a large smooth ovoid mass 40 x 29 mm in diameter projecting into the lumen from the base of the bladder. This mass is the hypertrophied median lobe of the prostate. The bladder wall is thickened due to muscular hypertrophy. This is an example of nodular hyperplasia of the prostate, resulting in acute or chronic urinary retention.

Note

Disproportionate enlargement of the median lobe is a common feature of nodular hyperplasia of the prostate. The projecting median lobe may occlude the internal urethral orifice on contraction of the bladder. See also R2 N2 Note.