Nodular Hyperplasia of Prostate

Clinical History

The specimen was an incidental autopsy finding in an 87 year old man with a 4 week history of obstructive jaundice due to carcinoma of the head of the pancreas.


The specimen is a bladder and prostate. The median and lateral lobes of the prostate are enlarged, and the median lobe projects above the internal urethral orifice. There is hypertrophy and trabeculation of the bladder wall.


Trabeculation of the bladder mucosa is a sign of chronic urinary outflow obstruction. The trabeculation is due to hypertrophy of smooth muscle bundles. See also R2 N3 Note.