SPHPM Seminar: Iron and Alzheimer's disease – What's the connection? From observational data to intervention studies

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Event Details

Date:
8 November 2017 at 12:32 am
Venue:
Ground floor conference rooms, 553 St Kilda Road, Melbourne VIC 3004
Campus:
Alfred
Open to:
ALL
Cost:
FREE
Categories:
Medicine, Nursing, Health Science; Public lectures; Seminars & Workshops

Description

Iron and Alzheimer's disease - What's the connection? From observational data to intervention studies

Professor Ashley Bush and Dr Scott Ayton – The Florey Institute of Neuroscience and Mental Health

Ashley Bush is Professor of Neuroscience and Psychiatry at The University of Melbourne, and Director of the Melbourne Centre for Dementia Research based at The Florey Institute of Neuroscience and Mental Health, currently listed in Thomson Reuters' "The World's Most Influential Scientific Minds". Dr Scott Ayton is an NHMRC-ARC Dementia Research Fellow and Deputy Director of the Melbourne Centre for Dementia Research based at The Florey Institute of Neuroscience and Mental Health and The University of Melbourne.

Iron could be one lesion that propels the syndromic progression of dementia but, until recently, the evidence linking brain iron with clinical deterioration in Alzheimer’s disease was lacking. Using a variety of methods (CSF ferritin and imaging, Quantitative Susceptibility Mapping-MRI and post mortem work, amongst others) they demonstrate data to support the therapeutic approach of lowering brain iron. They will test this in the 3D study – a phase IIb clinical trial that will identify whether lowering brain iron with the iron chelator deferiprone slows the progression of Alzheimer’s disease.


Event Contact

Name
A/Prof Anita Wluka
E-Mail
anita.wluka@monash.edu
Phone
+61 3 9903 0444
Organisation
Monash University, School of Public Health and Preventive Medicine