SPHPM Seminar: Iron and Alzheimer's disease – What's the connection? From observational data to intervention studies
- 8 November 2017 at 12:32 am
- Ground floor conference rooms, 553 St Kilda Road, Melbourne VIC 3004
- Open to:
- Medicine, Nursing, Health Science; Public lectures; Seminars & Workshops
Iron and Alzheimer's disease - What's the connection? From observational data to intervention studies
Professor Ashley Bush and Dr Scott Ayton – The Florey Institute of Neuroscience and Mental Health
Ashley Bush is Professor of Neuroscience and Psychiatry at The University of Melbourne, and Director of the Melbourne Centre for Dementia Research based at The Florey Institute of Neuroscience and Mental Health, currently listed in Thomson Reuters' "The World's Most Influential Scientific Minds". Dr Scott Ayton is an NHMRC-ARC Dementia Research Fellow and Deputy Director of the Melbourne Centre for Dementia Research based at The Florey Institute of Neuroscience and Mental Health and The University of Melbourne.
Iron could be one lesion that propels the syndromic progression of dementia but, until recently, the evidence linking brain iron with clinical deterioration in Alzheimer’s disease was lacking. Using a variety of methods (CSF ferritin and imaging, Quantitative Susceptibility Mapping-MRI and post mortem work, amongst others) they demonstrate data to support the therapeutic approach of lowering brain iron. They will test this in the 3D study – a phase IIb clinical trial that will identify whether lowering brain iron with the iron chelator deferiprone slows the progression of Alzheimer’s disease.
- A/Prof Anita Wluka
- +61 3 9903 0444
- Monash University, School of Public Health and Preventive Medicine