Engineering the Next Generation of Nanoparticle Drug Carriers

There have been significant advances in the treatment of diseases such as HIV, flu and cancer using nanoparticle therapies, however there is still a way to go before we have the optimal drug delivery system. The next generation of nanoparticle drug carriers will need to respond intelligently to biological stimuli to target the drugs where it is required. The aim of this project will be to develop self-assembled nanoparticles loaded with proteins and DNA and to engineer the release of the cargo precisely inside the cell. The project will involve polymer synthesis, materials characterization and live cell fluorescence imaging.

The project will focus on engineering nanoparticles in Dr Johnston’s lab, and will also involve working with Dr Georgina Such from the University of Melbourne synthesising polymers.