Rational design of chiral catalysts for asymmetric synthesis

Access to multi-stereocentre containing (sp3-rich) scaffolds is essential to improving outcomes in drug discovery, particularly in phenotypic-based approaches. This program focusses on combining modular chiral catalyst design and advanced theoretic methods to remove barriers to the synthetic preparation of sp3-rich compounds, including bioactive natural products with therapeutic potential.

Rational design of chiral catalysts for asymmetric synthesis

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