Using nanotechnology to unlock the secrets of biology

Nanoengineered drug carriers have the potential to revolutionise the treatment of a number of diseases. For maximum therapeutic efficiency, drugs not only need to be delivered to the right cells, but to the specific compartments within these cells where the drug is active. The aim of this project will be to understand the mechanisms of nanoparticle trafficking in cells using a combination of high-resolution fluorescence microscopy, live cell imaging and functional fluorescence assays. You will also work on functionalising nanoparticles to control their trafficking and localization within the cell.