Nanostructured mass spectrometry chips
We have developed nanostructured surfaces that allow the direct and quantitative analysis of small molecules in body fluids including saliva, urine, sweat, blood and breath by means of laser desorption ionisation mass spectrometry.
This platform technology has many exciting applications: we initially focussed on non-invasive illicit drug detection in collaboration with the Australian Federal Police, then started to pursue detection of doping substances funded by the World Anti-Doping Agency and now are also engaging in collaborations with clinicians to detect and quantify small molecular biomarkers for cancer and neurodegenerative disease. For example, lung cancer (LC) is the leading cause of cancer related deaths worldwide and there is not a synchronised method for detection/treatment. Our technology is conducive to enabling informed disease management through early LC detection directly from body fluids.
Several projects are available for interested Honours students.