Labs

Lab head

Lab name

Research areas

Professor Patrick Sexton

Metabolic G Protein-coupled Receptor Biology

Metabolic and endocrine disorders, neuropsychiatric disease, allosteric modulation, biased agonism, structural biology, chemical biology, integrated pharmacology, receptor trafficking, compartmentalised signalling

Professor Arthur Christopoulos

Analytical Neuropharmacology

Neuropsychiatric diseases, metabolic and endocrine disorders, cardiovascular disease, allosteric modulation, drug discovery, chemical biology, schizophrenia, Alzheimer’s disease, structural biology, biased agonism

Dr Betty Exintaris

Male Reproductive Pharmacology

Prostate, benign prostatic hyperplasia (BPH), lower urinary tract symptoms, smooth muscle, spontaneous activity, contractile activity, slow waves, metabolic and endocrine disorders, inflammation.

Professor Mark Febbraio
Cellular & Molecular Metabolism
Metabolic disease, obesity, inflammation, non-alcoholic steatohepatitis, liver cancer, ceramides & metabolism, chimeric cytokine proteins, treatment of age-related disease.
Dr Sebastian Furness
Receptor Transducer Coupling
Class B GPCRs, mechanisms of efficacy, molecular effector coupling, biased agonism, chemical biology, signal transduction, structural biology, integrated pharmacology, metabolic and endocrine disorders, diabetes, cancer

Dr Karen Gregory

Endocrine & Neuropharmacology

Neuropsychiatric diseases, schizophrenia, Alzheimer's disease, allosteric modulation, neuronal culture, cell signalling, chemical biology, structural biology, dimerization, mutagenesis

Dr Michelle Halls

Spatial Organisation of Signalling

Protein complexes, signal compartmentalisation, spatiotemporal signalling, cAMP, ERK, receptor trafficking, cancer

Dr John Haynes

Stem Cells & Neuroinflammatory Disease Modelling

Parkinson's disease, neuroinflammation, neurodegeneration, neuropsychiatric disease, neurodevelopment, Renal disease, Alport Syndrome, cardiovascular disease

Dr Chris Langmead

Molecular and Translational Drug Discovery - Servier Drug Discovery Program

Neuropsychiatric disease, inflammation, metabolic and endocrine disorders, drug discovery, orphan G protein-coupled receptors, high-throughout screening, hits-to-leads, translational biology, high content imaging, biased agonism

Dr Katie Leach

Endocrine & Neuropharmacology

Calcium sensing receptor, cell signalling, allosteric modulators, receptor structure-function, drug-receptor interactions, analytical/molecular pharmacology, biased agonism/ modulation, metabolic and endocrine disorders.

Dr Lauren May

Cardiac G protein-coupled Receptor Pharmacology

Cardiovascular disease, heart failure, ischaemia-reperfusion injury, G protein-coupled receptors, adenosine receptors, allosteric modulation, biased agonism, structural biology, molecular modelling, ligand-receptor interactions

Dr Daniel Poole

Integrated Neurogenic Mechanisms

Inflammation, Colitis, Neuroscience, Enteric Nervous System, Pain, Neuroimmune Interaction, Gastrointestinal Physiology, Glia, TRP Channels

A/Prof Erica Sloan

Cancer & Neural-Immune Regulation

Cancer, stress, symptoms, treatment, metastasis, molecular and cellular mechanisms, imaging, behaviour, mouse models.

Dr Celine Valant

Analytical Neuropharmacology

Neuropsychiatric disorders, asthma/COPD, endogenous and synthetic allosteric modulators, GPCRs

Dr Sab Ventura

Male Reproductive Pharmacology

Male contraception, benign prostatic hyperplasia, prostate cancer, vas deferens, adrenoceptors, purinoceptors.

A/Prof Paul White

Cardiac G protein-coupled Receptor Pharmacology

Cardiovascular disease, heart failure, ischaemia-reperfusion injury, G protein-coupled receptors, adenosine receptors, allosteric modulation, biased agonism, structural biology, molecular modelling, ligand-receptor interactions

A/Prof Denise Wootten

Metabolic G Protein-coupled Receptor Biology

Class B GPCRs, biased agonism, allosteric modulation, structural biology, chemical biology, receptor trafficking, signal transduction, integrated pharmacology, metabolic and endocrine disorders, diabetes.