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The Drug Discovery Biology Doctoral Program ensures that our graduates are not only specialists in their chosen scientific field, but also have an understanding of diverse topics, techniques and practices relevant to drug discovery. The doctoral program is completed over four years; the first year includes taught elements that constitute an advanced course in drug discovery alongside three rotational research projects, allowing students to explore potential doctoral research areas. This first year provides a strong grounding in biomedical research and facilitates the development of technical skills. The rotation program enables candidates to make an informed choice of their final area of research prior to commencement of their three-year project.

The Heart Failure Pharmacology laboratory specialises in the following experimental approaches -

  • in vivo models of diabetic cardiac disease
  • physiological in vitro and/or in vivo models of cardiac ischaemia
  • gene therapy and biochemical techniques
  • assessment of cardiac and vascular function
  • GPCR signalling fingerprints
  • detection of reactive oxygen species
  • histology and immunofluorescence
  • ELISA and immunoblotting

We offer five areas of research as full three-year PhD projects and for the first-year rotation program.

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1.     Targeting inflammation in the cardiac complications of diabetes

INSET Supervisors: Professor Rebecca Ritchie and Dr Miles De Blasio

2.     Targeting altered cardiac glucose metabolism in the cardiac complications of diabetes

INSET Supervisors: Professor Rebecca Ritchie and Dr Miles De Blasio

3.     Combining drug and gene therapy approaches to limit diabetes-induced cardiac fibrosis

INSET Supervisors: Professor Rebecca Ritchie and Dr Mitchel Tate

4.     Targeting inflammation and its resolution in the acute and chronic cardiac response to myocardial infarction

INSET Supervisors: Professor Rebecca Ritchie and Dr Helena Qin

5.     Nitroxyl-based therapies to overcome diabetes-induced impairments in cardiac NO signalling

INSET Supervisors: Professor Rebecca Ritchie and Dr Helena Qin