Skip to Content

Publications

Top five publications

..

Qin CX, May LT, Li R, Cao N, Rosli S, Deo M, Alexander AE, Horlock D, Bourke JE, Yang YH, Stewart AG, Kaye DM, Du XJ, Sexton PM, Christopoulos A, Gao XM, & Ritchie RH (2017). Small-molecule-biased formyl peptide receptor agonist compound 17b protects against myocardial ischaemia-reperfusion injury in mice. Nature Communications 8: 14232. Impact Factor: 12. Nature Communications is one of the most prestigious multidisciplinary journals published by the Nature Publishing Group in all areas of the biological, physical and chemical sciences. This publication also resulted in a correspondence letter published in Nature Communications the following year [Qin, C. X., May, L. T., Sexton, P. M., DeBono, A. J., Baell, J. B., Christopoulos, A., & Ritchie, R. H. (2018). Correspondence: Reply to 'Compound 17b and formyl peptide receptor biased agonism in relation to cardioprotective effects in ischaemia-reperfusion injury'. Nature Communications, 9: [530]. https://doi.org/10.1038/s41467-017-02656-0]

..

Qin CX, Yang YH, May L, Gao X, Stewart AG, Tu Y, Woodman OL, & Ritchie RH (2015). Cardioprotective potential of annexin-A1 mimetics in myocardial infarction. Pharmacology & Therapeutics 148: 47-65. Impact Factor: 11, Q1 in Pharmacology and Pharmacology (medical). Pharmacology & Therapeutics is among the top 10 most cited journals in pharmacology.

..

..

..

..

Jelinic M, Kahlberg N, Leo CH, Ng HH, Rosli S, Deo M, Li M, Finlayson S, Walsh J, Parry LJ, Ritchie RH, & Qin CX (2020). Annexin-A1 deficiency exacerbates pathological remodelling of the mesenteric vasculature in insulin-resistant, but not insulin-deficient, mice. British Journal of Pharmacology, 177: 1677-1691. https://doi.org/10.1111/bph.14927. Impact Factor: 7, Q1 in Pharmacology. Corresponding author. This discovery revealed for the first time that the anti-inflammatory protein Annexin-A1 is critical in regulating vascular remodelling in diabetes.

..

..

..

Deora GS#, Qin CX#, Vecchio EA, Debono AJ, Priebbenow DL, Brady RM, Beveridge J, Teguh SC, Deo M, May LT, Krippner G, Ritchie RH, & Baell JB (2019). Substituted Pyridazin-3(2 H)-ones as Highly Potent and Biased Formyl Peptide Receptor Agonists. Journal of Medicinal Chemistry, 62: 5242-5248. https://doi.org/10.1021/acs.jmedchem.8b01912. Impact Factor: 6, Q1 in Drug Discovery. #Joint first author. This study revealed the key chemical structure required for FPR activation, and showcases Dr Qin's multidisciplinary research output.

..

..

..

Qin CX, Anthonisz J, Leo CH, Kahlberg N, Velagic A, Li M, Jap E, Woodman OL, Parry LJ, Horowitz JD, Kemp-Harper BK, & Ritchie RH (2020). Nitric Oxide Resistance, Induced in the Myocardium by Diabetes, Is Circumvented by the Nitric Oxide Redox Sibling, Nitroxyl. Antioxidants and Redox Signaling, 32: 60-78. https://doi.org/10.1089/ars.2018.7706. Impact Factor: 6, Q1 in Endocrinology & Metabolism and Biochemistry & Molecular Biology. Corresponding author. This study highlighted the therapeutic potential of nitroxyl donors in a cardiac emergency.

..

..

..


..

Full List of Publications

 

...