Chemical biology

Chemical biology

Chemical Biology at DDB sits at the interface of biology and medicinal/synthetic chemistry. It uses small-molecule probes to interrogate specific biomolecular targets and pathways that are modulated by the particular probe.

Numerous projects focus on small molecules as novel allosteric modulators and/or signal pathway-biased ligands, either as unique biological tools or potential therapeutic hits/leads. These approaches are guided by our world-class expertise in analytical pharmacology and by close collaboration with the medicinal chemists at MIPS.

Research laboratories

Analytical Neuropharmacology Cardiac GPCR Pharmacology
 
Endocrine & Neuropharmacology  Male Reproductive Pharmacology
 
Metabolic GPCR Biology Molecular & Translational Drug Discovery
 
Receptor Transducer Coupling