Chemical biology

Chemical biology

Chemical Biology at DDB sits at the interface of biology and medicinal/synthetic chemistry. It uses small-molecule probes to interrogate specific biomolecular targets and pathways that are modulated by the particular probe.

Numerous projects focus on small molecules as novel allosteric modulators and/or signal pathway-biased ligands, either as unique biological tools or potential therapeutic hits/leads. These approaches are guided by our world-class expertise in analytical pharmacology and by close collaboration with the medicinal chemists at MIPS.

Research laboratories

Analytical NeuropharmacologyCardiac GPCR Pharmacology
 
Dr Celine Valant Prof Arthur Christopoulos   Dr Lauren May A/Prof Paul White
Endocrine & NeuropharmacologyMale Reproductive Pharmacology
 
Dr Katie Leach Dr Karen Gregory   Dr Sab Ventura Dr Betty Exintaris
Metabolic GPCR BiologyMolecular & Translational Drug Discovery
 
Prof Patrick Sexton A/Prof Denise Wootten   Dr Chris Langmead
Receptor Transducer Coupling
Dr Sebastian Furness