Integrated biology

Research at DDB extends findings from structural biology and cell-based systems to studies on the functions of receptors, ion channels and cytokines in physiological processes and mechanisms of disease. This includes investigating their regulation by endogenous and exogenous substances.

Our projects encompass studies of behaviour, cardiovascular function, metabolic homeostasis, inflammation, pain, tumour growth and metastasis. This work utilises state-of-the art approaches, including CRISPR-generated mutant mice, metabolic profiling, behavioural analyses and whole-animal imaging.

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Research laboratories

Analytical Neuropharmacology Cancer & Neural-Immune Regulation
 
Cardiac GPCR Pharmacology Cellular & Molecular Metabolism
 
Male Reproductive Pharmacology Metabolic GPCR Biology
 
Molecular & Translational Drug Discovery