Integrated biology

Research at DDB extends findings from structural biology and cell-based systems to studies on the functions of receptors, ion channels and cytokines in physiological processes and mechanisms of disease. This includes investigating their regulation by endogenous and exogenous substances.

Our projects encompass studies of behaviour, cardiovascular function, metabolic homeostasis, inflammation, pain, tumour growth and metastasis. This work utilises state-of-the art approaches, including CRISPR-generated mutant mice, metabolic profiling, behavioural analyses and whole-animal imaging.


Research laboratories

Analytical NeuropharmacologyCancer & Neural-Immune Regulation
Dr Celine Valant Prof Arthur Christopoulos   A/Prof Erica Sloan
Cardiac GPCR PharmacologyCellular & Molecular Metabolism
Dr Lauren May A/Prof Paul White   Prof Mark Febbraio
Male Reproductive PharmacologyMetabolic GPCR Biology
Dr Sab Ventura Dr Betty Exintaris   Prof Patrick Sexton A/Prof Denise Wootten
Molecular & Translational Drug Discovery
Dr Chris Langmead