Integrated biology

Research at DDB extends findings from structural biology and cell-based systems to studies on the functions of receptors, ion channels and cytokines in physiological processes and mechanisms of disease. This includes investigating their regulation by endogenous and exogenous substances.

Our projects encompass studies of behaviour, cardiovascular function, metabolic homeostasis, inflammation, pain, tumour growth and metastasis. This work utilises state-of-the art approaches, including CRISPR-generated mutant mice, metabolic profiling, behavioural analyses and whole-animal imaging.


Research laboratories

Analytical & Structural Neuropharmacology Cancer & Neural-Immune Regulation
Dr Celine Valant Dr David Thal Prof Arthur Christopoulos   A/Prof Erica Sloan
Cardiac GPCR Pharmacology Cellular & Molecular Metabolism
Dr Lauren May A/Prof Paul White    Prof Mark Febbraio
Heart Failure Pharmacology Integrated Neurogenic Mechanisms
Prof Rebecca Ritchie    Dr Simona Carbone Dr Daniel Poole Dr Nicholas Veldhuis
Male Reproductive Pharmacology Metabolic GPCR Biology
Dr Sab Ventura Dr Betty Exintaris    Prof Patrick Sexton A/Prof Denise Wootten
Molecular & Translational Drug Discovery 
Dr Chris Langmead