The DDB structural biology groups aim to understand the structure of macromolecules including G protein-coupled receptors, and how modifying this structure affects macromolecule function.
Our structural biology work encompasses a diverse array of mutational, molecular modelling, biophysical, crystallographic, cryo-electron microscopy and NMR studies. These aim to yield insights into the structure, function and dynamics of receptor proteins.
|Analytical Neuropharmacology||Cardiac GPCR Pharmacology|
|Endocrine & Neuropharmacology||Metabolic GPCR Biology|
|Receptor Transducer Coupling||Molecular & Translational Drug Discovery|