Structural biology

Structural biology

The DDB structural biology groups aim to understand the structure of macromolecules including G protein-coupled receptors, and how modifying this structure affects macromolecule function.

Our structural biology work encompasses a diverse array of mutational, molecular modelling, biophysical, crystallographic, cryo-electron microscopy and NMR studies. These aim to yield insights into the structure, function and dynamics of receptor proteins.

Research laboratories

Analytical Neuropharmacology Cardiac GPCR Pharmacology
 
Endocrine & Neuropharmacology  Metabolic GPCR Biology
 
Receptor Transducer Coupling Molecular & Translational Drug Discovery