Structural biology

Structural biology

The DDB structural biology groups aim to understand the structure of macromolecules including G protein-coupled receptors, and how modifying this structure affects macromolecule function.

Our structural biology work encompasses a diverse array of mutational, molecular modelling, biophysical, crystallographic, cryo-electron microscopy and NMR studies. These aim to yield insights into the structure, function and dynamics of receptor proteins.

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Research laboratories

Analytical & Structural Neuropharmacology Cardiac GPCR Pharmacology
 
Dr Celine Valant Dr David Thal Prof Arthur Christopoulos   Dr Lauren May A/Prof Paul White
Endocrine & Neuropharmacology Metabolic GPCR Biology
 
Dr Katie Leach Dr Karen Gregory    Prof Patrick Sexton A/Prof Denise Wootten
Molecular & Translational Drug Discovery Receptor Transducer Coupling
 
Dr Chris Langmead     Dr Sebastian Furness