Coronary heart disease kills more Australians than any other single disease. Many people survive myocardial infarction only to live shorter lives of reduced quality because of the damage to the myocardium that occurs during the infarction.
Heart failure, in which the damaged heart cannot eject sufficient blood, or sudden death due to electrical dysfunction in scarred regions of the heart, are common problems after myocardial infarction.
Our work in this area looks at protecting the heart muscle immediately after a myocardial infarction. We are currently identifying and developing G protein-coupled receptor ligands that show desired disease-specific signalling with reduced side effects.
|Analytical Neuropharmacology||Cardiac GPCR Pharmacology|
|Stem Cell Biology|