Pain and inflammation

Inflammation and painInflammation and pain are conserved protective mechanisms that are essential for survival. Inflammation, characterised by acute changes in the circulatory and immune systems, protects against infection. Pain allows avoidance of damaging stimuli.

Dysregulated chronic inflammation underlies diseases of global relevance — such as cardiovascular disease, cancer, diabetes, obesity and autoimmune diseases — and can cause chronic pain. Chronic inflammation and pain are major causes of human suffering, yet are poorly understood.

Research at DDB seeks to understand the basic mechanisms that control signalling of inflammation and pain, and determine whether defects in these regulatory mechanisms cause disease.


Research laboratories

Analytical & Structural Neuropharmacology Cellular & Molecular Metabolism
Dr Celine Valant Dr David Thal Prof Arthur Christopoulos   Prof Mark Febbraio
Integrated Neurogenic Mechanisms Male Reproductive Pharmacology
Dr Simona Carbone Dr Daniel Poole Dr Nicholas Veldhuis   Dr Sab Ventura Dr Betty Exintaris
Spatial Organisation of Signalling Stem Cell Biology
Dr Michelle Halls     Dr John Haynes