Kasiram Katneni

Dr Kasiram Katneni

Dr Kasiram Katneni

Research Officer
Centre for Drug Candidate Optimisation (CDCO)
Tel: +61 3 990 39147
Email: kasiram.katneni@monash.edu
CDCO Website


Kasiram Katneni is a Research Officer within the Biopharmaceutics Section of the Centre for Drug Candidate Optimisation (CDCO).  Kasiram specializes in pre-clinical DMPK and has more than 12 years' experience in preclinical drug discovery and development. He worked as a Senior Research Associate  in  Dr.  Reddy's Research Foundation (Hyderabad, India) before moving to Australia where he completed his Ph.D. in Pharmaceutics at the Faculty of Pharmacy and Pharmaceutical Sciences, Monash University. Kasiram joined the CDCO in 2007. His role focusses on defining the in vitro ADME properties of new  drug  candidates,  including permeability, metabolism and drug-drug interactions. He has been involved in the development of reliable in vitro screening methods and supported preclinical optimization efforts across different drug discovery projects. Kasiram enjoys working on projects across different therapeutic  areas  and  seeing the direct impact resulting from work for neglected diseases. Outside of work, his interests include going to the gym, listening to music, reading and cooking.

Recent Publications

Nilsen, A., Miley, G.P., Forquer, I.P., Mather, M.W., Katneni, K., Li, Y., Pou, S., Pershing, A.M., Stickles, A.M., Ryan, E., Kelly, J.X., Doggett, J.S., White, K.L., Hinrichs, D.J., Winter, R.W., Charman, S.A., Zakharov, L.N., Bathurst, I.C., Burrows, J., Vaidya, A.B., Riscoe, M.K., 2014, Discovery,  synthesis,  and  optimization of antimalarial 4(1H)-quinolone-3-diarylethers, Journal of Medicinal Chemistry [P], vol 57, issue 9, American Chemical Society, Washington DC USA, pp. 3818-3834.

Carroux, C.J., Rankin, G.M., Moeker, J., Bornaghi, L.F., Katneni, K., Morizzi, J., Charman, S.A., Vullo, D., Supuran, C.T., Poulsen, S., 2013, A prodrug approach toward cancer-related carbonic anhydrase inhibition, Journal of Medicinal Chemistry [P], vol 56, issue 23, ACS Publications, Washington DC USA, pp. 9623-9634.

Murugesan, D., Mital, A., Kaiser, M., Shackleford, D., Morizzi, J., Katneni, K., Campbell, M., Hudson, A., Charman, S.A., Yeates, C., Gilbert, I.H., 2013, Discovery and structure-activity relationships of pyrrolone antimalarials, Journal of Medicinal Chemistry [P], vol 56, issue 7, ACS Publications, Washington DC USA, pp. 2975-2990.

Wang, X., Dong, Y., Wittlin, S., Charman, S.A., Chiu, F.C.K., Chollet, J., Katneni, K., Mannila, J.M., Morizzi, J., Ryan, E., Scheurer, C., Steuten, J.A., Santo Tomas, J., Snyder, C., Vennerstrom, J., 2013, Comparative antimalarial activities and ADME profiles of ozonides (1,2,4-trioxolanes) OZ277,  OZ439,  and  their 1,2-dioxolane, 1,2,4-trioxane, and 1,2,4,5-tetraoxane isosteres, Journal of Medicinal Chemistry [P], vol 56, issue 6, ACS Publications, Washington DC USA, pp. 2547-2555.

Carroux, C.J., Moeker, J., Motte, J., Lopez, M., Bornaghi, L.F., Katneni, K., Ryan, E., Morizzi, J., Shackleford, D., Charman, S.A., Poulsen, S., 2013, Synthesis of acylated glycoconjugates as templates to investigate in vitro biopharmaceutical properties, Bioorganic & Medicinal Chemistry Letters [P], vol 23, issue 2, Pergamon-Elsevier, Oxford UK, pp. 455-459.