Rationally optimised antibiotic dosing strategies to target resistant bacterial 'superbugs'

‘Superbugs' resistant to all available antibiotics in standard monotherapy are among the most serious threats to human health. At the same time there is a lack of new antibiotics. Individualised, precision antibiotic dosing strategies in optimised monotherapies or combinations provide a tangible and highly promising option to combat 'superbugs' by achieving maximised bacterial killing and suppression of resistance.

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