Targeted nanomedicines for controlled delivery of therapeutics

We all have seen the potential of nanomedicine in solving global needs, like their important role protecting and delivering the mRNA-based vaccines against COVID-19. This project aims to investigate how nanomedicines delivering drugs, RNA therapeutics or peptides can be made more effective by targeting only specific tissues and/or cell populations. The student will investigate different tissue and cell-targeting strategies such as using antibodies, aptamers and/or nanobodies.

This project will involve basic wet chemistry synthesis, as well as materials characterisation by DLS, FTIR, electron microscopy, and fluorescence spectroscopy. Interactions of the nanoparticles with cells and tissues will also be investigated using cell-based assays, molecular biology techniques, live cell microscopy and flow cytometry.