Mycoplasma testing

Mycoplasma contamination does not alter the appearance of media and cannot be detected by light microscopy. Mycoplasma contamination of cell cultures can cause chromosomal aberrations, disrupt nucleic acid synthesis, change membrane antigenicity, inhibit cell proliferation and metabolism, decrease transfection rates, change gene expression profiles, and even bring about cell death. MATF offers either a PCR or a sensitive kit-based detection service for mycoplasma. If your cells are positive, we can treat them with Plasmocure which has been shown to be effective in removing mycoplasma from over 90% of cell lines in a recent study

(Molla Kazemiha V, Azari S, Habibi-Anbouhi M, Amanzadeh A, Bonakdar S, Shokrgozar MA, Mahdian R. Effectiveness of Plasmocure™ in Elimination of Mycoplasma Species from Contaminated Cell Cultures: A Comparative Study versus other Antibiotics. Cell J. 2019 Jul;21(2):143-149. PMID: 30825287)