9.4T MRI

The Bruker 9.4T animal magnetic resonance imaging (MRI) system is a flexible and adaptable MRI scanner for preclinical imaging and research. It is located at our Clayton site and is suitable for small animal studies, with the ability to image objects as large as 7cm in diameter and as small as 100 microns.

Benefits of 9.4T MRI

• Intuitive user interface and a flexible programming environment with the ability to carry out a wide range of preclinical imaging functions
• The ultra high magnetic field provides structural and functional images with higher resolution in comparison with clinical MRI

Capabilities

• Respiratory and cardiac gated MRI
• MRI guided focused ultrasound (MRgFUS)
• Resolution as high as 35 microns

Research applications

• Anatomical and functional MRI in neuroscience
• Angiography in circulation
• Relaxivity for molecular imaging
• Cardiovascular (CV) profiling
• Brain molecular imaging
• Abdominal molecular imaging
• Cardiovascular molecular imaging
• Muscular molecular imaging
• Articular molecular imaging
• Dynamic molecular imaging
• Magnetic particle imaging (ex-vivo and in-vivo)
• Soft tissue differentiation.
• Perfusion and metabolism functional MR imaging
• Contrast enhanced imaging

9.4T MRI technical specifications

• Dual gradient coils
• Mouse and rat head array and surface coils for brain imaging
• Mouse and rat cardiac array coils for heart imaging
• Array coil for marmoset brain imaging
• 40mm 19F/1H dual channel fluorine imaging coil for mouse or samples
• 35mm volume coil for high-resolution mouse head/body or sample imaging
• 72mm volume coil for rat body or sample imaging
• 90mm and 86mm radio frequency transmit and receive coils
• Suitable isoflurane anaesthesia and animal monitoring system and heater to maintain animal temperature during the scan
• Full range of beds to cater for most species and samples

Compatible equipment

Visit the MR compatible equipment page for details on compatible equipment.

Additional support

When using the 9.4T MRI system, an experienced operator will run your scans to ensure optimal imaging results. We will also prepare your samples and live animals for imaging if required.

There is also the possibility of conducting longitudinal studies and using the same animal for the whole study period. This results in using a smaller number of animals during the study and getting more reliable outcomes for publications. Contact the Preclinical Support team for more information.