PET-SPECT-CT

Inveon PET-SPECT-CT small animal scanner

The Inveon Multimodality System is a versatile platform for laboratory animal CT, SPECT, and PET studies on a single integrated gantry.

The system can be configured for PET-CT, SPECT-CT, PET-SPECT-CT or CT only.

Benefits of PET-SPECT-CT

  • Fused 3D imaging of multiple static or dynamic volumes of each imaging modality combinations, with the ability to perform complex volumetric segmentation for quantification
  • Image acquisition controlled from physiological inputs
  • Integrated video system enhances animal positioning and monitoring

Capabilities

  • The system can be configured for PET-CT, SPECT-CT, PET-SPECT-CT or CT only
  • The large area CT system has a field of view up to 10cm x 10cm and resolution down to 20 microns
  • The PET system can deliver 1.4mm FWHM spatial resolution, and a maximum field of view of 10cm x 30cm
  • Whole mouse and rat SPECT studies are possible using gamma rays ranging in energy from 30 to 300 keV, with automated zoom for optimising the field of view
  • Fused 3D imaging of multiple static or dynamic volumes of each imaging modality combinations, with the ability to perform complex volumetric segmentation for quantification

Research applications

  • Oncology
  • Bone disease
  • Body metabolism
  • Antibody and isotope tracking
  • Soft versus dense tissue differentiation
  • Quantification and qualification analysis
  • Static, dynamic and kinetic acquisition and analysis
  • Contrast enhanced imaging

PET-SPECT-CT technical specifications

  • Respiratory gated protocols suitable for high resolution lung scans
  • Ability to scan more than one animal at the same time
  • Portable isofluorane anaesthesia system for rodents, animal warming pallets, and integrated monitoring of temperature, ECG and respiration
  • Image acquisition can be controlled from physiological inputs and an integrated video system enhances animal positioning and monitoring

Additional support

Our Preclinical Support Team can provide valuable guidance and our Administrative Team can help you navigate the relevant procedures.

Research integrating CT at MBI and synchrotron

Researchers from the University of Wollongong's Centre for Medical Radiation Physics (CMRP) - pictured below - have integrated their brain cancer research using personalised synchrotron microbeam radiation therapy (MRT) at the Australian Synchrotron with CT scanning at Monash Biomedical Imaging. As part of their research, rat models underwent CT imaging with MBI's Siemens Inveon PET/CT scanner to visualise tumour against normal brain tissue before MRT was conducted.

MBI's location next to the Australian Synchrotron has enabled us to create the only integrated synchrotron imaging and multi-modality (MRI/PET/SPECT) biomedical imaging research facility in the world.

Read more about the CMRP's research and published research in Nature Scientific Reports.

University of Wollongong researchers