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Dunstone lab publications

Selected highlight publications

1. Siew Siew Pang, Charles Bayly-Jones, Mazdak Radjainia, Bradley A. Spicer, Ruby H.P. Law, Adrian W. Hodel, Sue M. Ekkel, Paul J. Conroy, Georg Ramm, Hariprasad Venugopal, Phillip I. Bird, Bart W. Hoogenboom, Ilia Voskoboinik, Yann Gambin, Emma Sierecki, Michelle A. Dunstone, James C. Whisstock. The structure of macrophage-expressed gene 1 a phagolysosome immune effector that is activated upon acidification. Nat Commun (in press).

2. Siew Siew Pang, Charles Bayly-Jones, Mazdak Radjainia, Bradley A. Spicer, Ruby H. P. Law, Adrian W. Hodel, Edward S. Parsons, Susan M. Ekkel, Paul J. Conroy, Georg Ramm, Hariprasad Venugopal, Phillip I. Bird, Bart W. Hoogenboom, Ilia Voskoboinik, Yann Gambin, Emma Sierecki, Michelle A. Dunstone & James C. Whisstock, 2019, The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1, Nat Commun (10): 4288.

3. Dudkina NV, Spicer BA, Reboul CF, Conroy PJ, Lukoyanova N, Elmlund H, Law RH, Ekkel SM, Kondos SC, Goode RJ, Ramm G, Whisstock JC, Saibil HR, Dunstone MA. 2016. Structure of the poly-C9 component of the complement membrane attack complex. Nat Commun (7):10588.

4. Lukoyanova N, Kondos SC, Farabella I, Law RH, Reboul CF, Caradoc-Davies TT, Spicer BA, Kleifeld O, Traore DA, Ekkel SM, Voskoboinik I, Trapani JA, Hatfaludi T, Oliver K, Hotze EM, Tweten RK, Whisstock JC, Topf M, Saibil HR, Dunstone MA. 2015. Conformational changes during pore formation by the perforin-related protein pleurotolysin. PLoS Biol. 13(2):e1002049.

5. Reboul CF, Whisstock JC, Dunstone MA. 2014. A new model for pore formation by cholesterol-dependent cytolysins. PLoS Comput Biol. 10(8):e1003791.

6. Reboul CF, Mahmood K, Whisstock JC, Dunstone MA. 2012. Predicting giant transmembrane β-barrel architecture. Bioinformatics. 28(10):1299-302.

7. Rosado CJ, Buckle AM, Law RH, Butcher RE, Kan WT, Bird CH, Ung K, Browne KA, Baran K, Bashtannyk-Puhalovich TA, Faux NG, Wong W, Porter CJ, Pike RN, Ellisdon AM, Pearce MC, Bottomley SP, Emsley J, Smith AI, Rossjohn J, Hartland EL, Voskoboinik I, Trapani JA, Bird PI, Dunstone MA, Whisstock JC. 2007. A common fold mediates vertebrate defense and bacterial attack. Science. 317(5844):1548-51.

Additional publications

A full list of Dunstone Lab publications can be viewed on PubMed.