Chopin Laboratory
Dendritic cell transcriptional regulation
Dendritic cell transcriptional regulation
We aim to uncover the molecular mechanisms underpinning the differentiation of dendritic cells, key immune sentinels that orchestrate protective immune responses against pathogens or cancers, so that we can bring forward the next-generation of dendritic cell-based vaccines to bolster cancer immunotherapy.
We're part of the Monash Biomedicine Discovery Institute, and a member of the Cancer and Immunity Programs, and the Department of Biochemistry and Molecular Biology.
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We aim to exploit our expertise in cellular and molecular immunology to provide a strong rationale for the continued development and clinical assessment of the next-generation dendritic cell-based vaccines in cancer immunotherapy.
Dendritic cells are immune sentinels that play an essential role in mounting an immune response against pathogens or cancers. To face the variety of challenges, DCs have evolved into phenotypically and functionally distinct subsets. Our program of research aims to identify key regulators of DC homeostasis and to exploit their unique functional attributes to boost immune responses to conventional vaccines and cancer treatments.
We are committed to excellence in research.
We're always interested in collaborating with bright and motivated researchers, clinicians and industry. Whether you want to research, study or partner with us to accelerate our discoveries, find out about the work we do.