De Nardo Group
Monash Biomedicine Discovery Institute

De Nardo Group publications

Selected highlight publications

    Ullah TR*, Johansen MD*, Balka KR, Ambrose RL, Gearing LJ, Roest J, Vivian JP, Sapkota S, Jayasekara WSN, Wenholz DS, Aldilla VR, Zeng J, Miemczyk S, Nguyen DH, Hansbro NG, Venkatraman R, Kang JH, Pang ES, Thomas BJ, Alharbi AS, Rezwan R, O'Keeffe M, Donald WA, Ellyard JI, Wong W, Kumar N, Kile BT, Vinuesa CG, Kelly GE, Laczka OF, Hansbro PM**, De Nardo D**, Gantier MP**. Pharmacological inhibition of TBK1/IKKε blunts immunopathology in a murine model of SARS-CoV-2 infection. Nat Commun. 2023 Sep 18;14(1):5666. doi: 10.1038/s41467-023-41381-9. * denotes co-first author. ** denotes co-senior author.
  • Balka KR, Venkatraman R, Saunders TL, Shoppee A, Pang ES, Magill Z, Homman-Ludiye J, Huang C, Lane RM, York HM, Tan P, Schittenhelm RB, Arumugam S, Kile BT, O'Keeffe M, De Nardo D. Termination of STING responses is mediated via ESCRT-dependent degradation. EMBO J. 2023 Jun 15;42(12):e112712. doi: 10.15252/embj.2022112712.
  • Balka KR, De Nardo D. Molecular and spatial mechanisms governing STING signalling. FEBS J. 2021 Oct;288(19):5504-5529. DOI: 10.1111/febs.15640

  • Balka KR, Louis C, Saunders TL, Smith AM, Calleja DJ, D'Silva DB, Moghaddas F, Tailler M, Lawlor KE, Zhan Y, Burns CJ, Wicks IP, Miner JJ, Kile BT, Masters SL, De Nardo D. TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells. Cell Rep. 2020 Apr 7;31(1):107492. DOI: 10.1016/j.celrep.2020.03.056
  • Balka KR, De Nardo D. Understanding early TLR signaling through the Myddosome. J Leukoc Biol. 2019 Feb;105(2):339-351. DOI: 10.1002/JLB.MR0318-096R
  • De Nardo D, Balka KR, Cardona Gloria Y, Rao VR, Latz E, Masters SL. Interleukin 1 receptor-associated kinase 4 (IRAK4) plays a dual role in Myddosome formation and Toll-like receptor signalling. J Biol Chem. 2018 Sep 28;293(39):15195-15207. DOI: 10.1074/jbc.RA118.003314
  • Labzin LI, Schmidt SV, Masters SL, Krebs W, Klee K, Beyer M, Lütjohann D, Stahl R, Schultze JL, Latz E, De Nardo D. ATF3 is a key regulator of macrophage IFN responses. J Immunol.2015 Nov 1;195(9):4446-55. Epub 2015 Sep 28. DOI: 10.4049/jimmunol.1500204

  • De Nardo D. Toll-like receptors: activation, signalling and transcriptional modulation. Cytokine. 2015 Aug;74(2):181-9. DOI: 10.1016/j.cyto.2015.02.025

  • De Nardo D, Labzin LI, Kono H, Seki R, Schmidt SV, Beyer M, Xu D, Zimmer S, Lahrmann C, Schilberg FA, Vogelhuber J, Kraut M, Ulas T, Kerksiek A, Krebs W, Bode N, Grebe A, Fitzgerald ML, Hernandez NJ, Williams BRG, Knolle PA, Kneiling M, Rocken M, Lutjohann D, Wright SD, Schultze JL, Latz E. High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via transcriptional regulator ATF3. Nat Immunol. 2014 Feb;15(2):152-60. DOI: 10.1038/ni.2784
  • De Nardo D, Latz E. NLRP3 inflammasomes link inflammation and metabolic disease. Trends Immunol.2011 Aug;32(8):373-9. DOI: 10.1016/j.it.2011.05.004

Additional publications

A full list of De Nardo Group publications can be viewed on PubMed.