Goode Lab
Monash Biomedicine Discovery Institute

Goode Lab research

Collaborations | Student research projects | Publications

About Dr David Goode

Dr. Goode is a Senior Lecturer and head of the Cancer Bioinformatics and Tumour Evolution Lab in the Monash University Dept of Biochemistry & Molecular Biology  and the Monash Biomedicine Discovery Institute.

Dr Goode completed his PhD in Genetics at Stanford University before working for several years at the Peter MacCallum Cancer Centre. He has received funding from the NHRMC, MRFF, Victorian Cancer Agency and the CASS Foundation. His research has appeared in Science, Nature Genetics, Lancet Oncology, PNAS, Genome Biology and eLife.

Our research

Current projects

Visit Dr Goode's Monash research profile to see a full listing of current projects.

Research activities

  • Therapy resistance in advanced and metastatic prostate cancer
  • Tumour immune microenvironment and disease progression in brain cancer (glioma)
  • Molecular comparisons of cancers between ancestry groups
  • Predicting evolutionary trajectories of tumours


Techniques/expertise

  • Analysis of bulk, single-cell and spatial transcriptomics
  • Mapping the tumour immune microenvironment with multiplex immunohistochemistry
  • Machine learning to identify molecular features predictive of tumour types and response to treatment
  • Gene regulatory network analysis
  • Mathematical modelling of tumour evolution
  • Prediction and characterization of functional genetic variants and somatic mutations

Disease models

  • Patient derived xenografts and organoids

Collaborations

We collaborate with many scientists and research organisations around the world. Some of our more significant collaborators are listed below. Click on the map to see the details for each of these collaborators (and you'll be able to dive into specific publications and outputs).

Key collaborators include:

  • The Prostate Cancer Research Program at Monash University
  • The Brain Cancer Centre at the Walter and Eliza Hall Institute
  • Eastern Health Oncology
  • Peninsula Health Oncology
  • The Computational Biology Program at the Peter MacCallum Cancer Centre

The Cancer Bioinformatics and Tumour Evolution Lab is a member of the Melbourne Urological Research Alliance (MURAL).

Our consumer representative partners provide valuable contributions to the research and education of the members of the CBTE Lab.

Student research projects

The Goode Lab offers a variety of Honours, Masters and PhD projects for students interested in joining our Lab. There are also a number of short term research opportunities available.

Please visit Supervisor Connect to explore the projects currently available in our Lab.