Knott lab publications

Selected highlight publications

1. Fozouni, P., Son, S., Díaz de León Derby, M., Knott, GJ., Gray, CN., D’Ambrosio, MV., Zhao, C., Switz, NA., Kumar., GR., Stephens, SI., Boehm, D., Tsou, CL., Shu, J., Bhuiya, A., Armstrong, M., Harris, AR., Chen, PY., Osterloh, JM., Meyer-Franke, A., Joehnk, B., Walcott, K., Sil, A., Langelier, C., Pollard, KS., Crawford, ED., Puschnik, AS., Phelps, M., Kistler, A., DeRisi, JL., Doudna, JA., Fletcher, DA., and Ott, M. (2021) Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy.Cell. 184, 323-333.

2. Lapinaite, A*., Knott, GJ*., Palumbo, CM., Lin-Shiao, E., Richter, MF., Zhao, KT., Beal, PA., Liu, DR and Doudna, JA. (2020) DNA capture by a CRISPR-Cas9 guided adenosine base editor. Science. 369, 566-571. (*Equal Contribution).

3. Knott, GJ., Thornton, BW., Lobba, MJ., Liu, JJ., Al-Shayeb, B., Watters, KE., and Doudna, JA. (2019) Broad spectrum enzymatic inhibiton of CRISPR-Cas12a. Nature Structural and Molecular Biology. 26, 315-321.

4. Knott, GJ., & Doudna J.A. (2018) CRISPR-Cas guides the future of genetic engineering. Science. 361, 866-869.

5. Knott, GJ., East-Seletsky, A., Cofsky, JC., Holton, JM., Charles, E., O’Connell, MR., and Doudna, JA. (2017) Guide bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme. Nature Structural and Molecular Biology. 24, 825-833.

Additional publications

A full list of Knott Lab publications can be viewed on PubMed.