Lazarou Laboratory
Autophagy and Mitochondrial Quality Control
Welcome to the Lazarou Lab
Our lab investigates the molecular mechanisms of PINK1/Parkin mitophagy and how it works with mitochondrial repair pathways to maintain healthy mitochondria. Given the fundamental importance of autophagy to life, our research also aims to understand the factors and processes that govern autophagy.
We're part of the Monash Biomedicine Discovery Institute, and a member of the Neuroscience, Immunity, and Metabolism, Diabetes & Obesity Programs, and the Department of Biochemistry and Molecular Biology.
Dr Michael Lazarou
Deputy Head (Strategy), Neuroscience Program
My global research connections, partners and funding can be viewed on my Monash Research Profile.
If you are a student interested in doing research in our lab, visit Supervisor Connect.
Click the links below to connect with me on ORCID, Google Scholar and LinkedIn.
Our research
Parkinson’s disease (PD) is one of the most common of the neurodegenerative disorders, affecting 1-2% of the population worldwide. Multiple lines of evidence place mitochondrial dysfunction as a central player in the pathogenesis of sporadic PD, and studies of genes associated with familial PD demonstrate convergent pathways involving oxidative stress and mitochondrial dysfunction. Our research is focused on understanding how human cells maintain mitochondrial health via the repair or removal of damaged mitochondria.
Lab members
We are committed to excellence in research.
Join Our Lab
We're always interested in collaborating with bright and motivated researchers, clinicians and industry. Whether you want to research, study or partner with us to accelerate our discoveries, find out about the work we do.