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McArthur Group

Mitochondria, Cell Death & Immunity

Welcome to the McArthur Group

Our group aims to understand the dynamic interplay between mitochondria, cell death and disease, with a focus on the immune responses to mitochondrial changes and aberrant cell death.

We're part of the Monash Biomedicine Discovery Institute, and a member of the Metabolism, Diabetes and Obesity, and Immunity Programs, and the Department of Biochemistry and Molecular Biology.

Dr Kate McArthur

My global research connections, partners and funding can be viewed on my Monash Research Profile.

If you are a student interested in doing research in our lab, visit Supervisor Connect.

Click the links below to connect with me on X (formerly Twitter), ORCID, Google Scholar and LinkedIn.

Our research

Mitochondria more than just “the powerhouse of the cell”. They are fascinating, highly dynamic organelles that carry out an array of cellular functions; all the while sitting at the crossroads of cellular fate – mitochondria can release the power for life, and just as easily unleash the machineries of death. Our group explores the following questions:

  • What is the physiological relevance of mitochondrial herniation & how is it kept in check?

  • What are the molecular mechanisms of mtDNA release & how does mitochondrial ultrastructure regulate this process?

  • How does mtDNA contribute to disease?

Group members

The McArthur Group functions alongside the Formosa Group, as a collaborative and integrated unit within the Lab of Professor Mike Ryan, the Biochemistry and Molecular Biology Department, and the Monash Biomedicine Discovery Institute.

Publications

View our chosen highlighted key publications.

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News

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Join Our Lab

We're always interested in collaborating with bright and motivated researchers, clinicians and industry. Whether you want to research, study or partner with us to accelerate our discoveries, find out about the work we do.

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