McGowan lab publications

Selected highlight publications

1. Yang, W., Riley, BT., Lei, X., Porebski, BT., I Kass, I., Buckle, AM., & S McGowan 2018. Mapping the pathway and dynamics of bestatin inhibition of the Plasmodium falciparum M1 aminopeptidase, PfA-M1. ChemMedChem, 13,2504-2513. [invited cover illustration, 23/2018].

2. Mistry S, Drinkwater N, Ruggeri C, Kannan Sivaraman K, Loganathan S, Fletcher S, Drag M, Paiardini A, Avery V, Scammells P & McGowan S. 2014. A Two-pronged Attack: Dual Inhibition of M1 and M17 Metalloaminopeptidases by a Novel Series of Hydroxamic acid-based Inhibitors. J Med Chem 57(21), 9168-9183.

3. McGowan S, Buckle AM, Mitchell MS, Hoopes JT, Gallagher DT, Heselpoth RD, Shen Y, Reboul CF, Law RH, Fischetti VA, Whisstock JC, and Nelson DC. 2012. X-ray crystal structure of the streptococcal specific phage lysin PlyC. Proc Natl Acad Sci USA 109, 12752- 12757.

4. McGowan S, Oellig CA, Birru WA, Caradoc-Davies TT, Stack CM, Lowther J, Skinner-Adams T, Mucha A, Kafarski P, Grembecka J, Trenholme KR, Buckle AM, Gardiner DL, Dalton JP, and Whisstock JC. 2010. Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases. Proc Natl Acad Sci USA 107, 2449-2454.

5. McGowan S, Porter CJ, Lowther J, Stack CM, Golding SJ, Skinner-Adams TS, Trenholme KR, Teuscher F, Donnelly SM, Grembecka J, Mucha A, Kafarski P, Degori R, Buckle AM, Gardiner DL, Whisstock JC, and Dalton JP. 2009. Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase. Proc Natl Acad Sci USA 106, 2537-2542.

Additional publications

A full list of McGowan Lab publications can be viewed on Google Scholar.