Peleg Laboratory
Mechanisms Of Disease Caused By Hospital-Acquired Pathogens
Welcome to the Peleg Lab
Our research program focuses on the mechanisms of pathogenesis of important hospital-acquired pathogens and the identification of novel therapeutic targets. More specifically, multidrug-resistant Gram-negative bacteria, including Acinetobacter baumannii, and the Gram-positive bacterial pathogen, Staphylococcus aureus.
We're part of the Monash Biomedicine Discovery Institute and a member of the Infection Program and the Department of Microbiology.
Professor Anton Peleg
My global research connections, partners and funding can be viewed on my Monash Research Profile.
If you are a student interested in doing research in our lab, visit Supervisor Connect.
Click the links below to connect with me on ORCID and Google Scholar.
Our research
We investigate the molecular mechanisms underlying bacterial virulence, antimicrobial resistance (AMR) and host–pathogen interactions, with a primary focus on challenging Gram-negative (e.g. Acinetobacter baumannii, Pseudomonas aeruginosa and carbapenem-resistant Enterobacterales) and Gram-positive (e.g. Staphylococcus aureus) AMR pathogens. We combine bacterial genetic techniques with exciting in vitro, ex vivo and in vivo infection model systems (mammalian and non-mammalian, e.g. zebrafish) to characterise the role of novel genes in virulence, persistence and adaptation, and to investigate host immune responses, specifically neutrophil function. We also explore novel therapeutic approaches to combat bacterial and biofilm infections, including bacteriophage therapy and the development of innovative antimicrobial strategies. Our overarching goal is to advance understanding of bacterial pathogenesis and host–pathogen interactions and identify new targets and approaches for the treatment of infectious diseases.
Lab members
We are committed to excellence in research.
Join Our Lab
We're always interested in collaborating with bright and motivated researchers, clinicians and industry. Whether you want to research, study or partner with us to accelerate our discoveries, find out about the work we do.