Ramm Laboratory
Advanced Cellular Imaging
Welcome to the Ramm Lab
We are studying cellular architecture and intracellular trafficking with the use of cryo-electron tomography and correlative light and electron microscopy.
We're part of the Monash Biomedicine Discovery Institute, and a member of the Cancer, Immunity and Metabolism, Diabetes & Obesity Programs, and the Department of Biochemistry and Molecular Biology.
Associate Professor Georg Ramm
My global research connections, partners and funding can be viewed on my Monash Research Profile.
If you are a student interested in doing research in our lab, visit Supervisor Connect.
Click the links below to connect with me on Twitter, ORCID, Google Scholar and LinkedIn.
Our research
Our lab is focused on high-resolution imaging of cellular architecture and intracellular trafficking. We are the first in Australia to use cryo-tomography (on Titan Krios) in combination with cryo-focused ion beam milling (cryo-FIB on cryo-Helios) to reveal cellular structures at the highest resolution. We focus on fundamental cell biological problems that are relevant to human diseases. This includes the intracellular degradation of organelles by autophagy and mitophagy, mitochondrial ultrastructure and dynamics in healthy and stressed cells, and cellular structural changes during cell death.
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1. Cellular cryo-tomography
We are developing and applying cryo tomography to understand fundamental cell biological processes.
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2. Cell stress response
We focus on how mitochondrial structure changes during cellular stress responses such as apoptosis or autophagy.
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3. Correlative microscopy
We develop new techniques for standard temperature and cryo correlative light and electron microscopy and apply these to fundamental questions in cell biology.
Lab members
We are committed to excellence in research.
Join Our Lab
We're always interested in collaborating with bright and motivated researchers, clinicians and industry. Whether you want to research, study or partner with us to accelerate our discoveries, find out about the work we do.