Spanswick
Laboratory
Obesity and Metabolic
Neurophysiology
Obesity and Metabolic
Neurophysiology
We're part of the Monash Biomedicine Discovery Institute, and a member of the Metabolism, Diabetes & Obesity and Neuroscience Programs, and the Department of Physiology.
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One nutrient that is controlled and maintained within narrow limits is glucose. Glucose levels are maintained by a network of interacting peripheral and central glucose-sensing systems. Consequently understanding the fundamental mechanisms by which function-specific glucose-sensing neurons and networks detect, respond and formulate appropriate output and if and how they are subject to dysfunction in obesity and diabetes is critical to developing future intervention strategies. We employ an electrophysiological approach to identify mechanisms by which function-specific neurones and circuits detect changes in energy status to co-ordinate appropriate behavioural responses and how they change depending on the energy status of the organism.
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