Skip to Content

Whisstock lab publications

Selected highlight publications

1. Human Plasminogen Exacerbates Clostridioides difficile Enteric Disease and Alters the Spore Surface.
Awad MM, Hutton ML, Quek AJ, Klare WP, Mileto SJ, Mackin K, Ly D, Oorschot V, Bosnjak M, Jenkin G, Conroy PJ, West N, Fulcher A, Costin A, Day CJ, Jennings MP, Medcalf RL, Sanderson-Smith M, Cordwell SJ, Law RHP, Whisstock JC, Lyras D.

2. The first transmembrane region of complement component-9 acts as a brake on its self-assembly.
Spicer BA, Law RHP, Caradoc-Davies TT, Ekkel SM, Bayly-Jones C, Pang SS, Conroy PJ, Ramm G, Radjainia M, Venugopal H, Whisstock JC, Dunstone MA.Nat Commun. 2018 Aug 15;9(1):3266. doi: 10.1038/s41467-018-05717-0.

3. Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3.
Traore DAK, Wisniewski JA, Flanigan SF, Conroy PJ, Panjikar S, Mok YF, Lao C, Griffin MDW, Adams V, Rood JI, Whisstock JC.Nat Commun. 2018 Sep 13;9(1):3732. doi: 10.1038/s41467-018-06096-2.

4. The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
Pang SS, Bayly-Jones C, Radjainia M, Spicer BA, Law RHP, Hodel AW, Parsons ES, Ekkel SM, Conroy PJ, Ramm G, Venugopal H, Bird PI, Hoogenboom BW, Voskoboinik I, Gambin Y, Sierecki E, Dunstone MA, Whisstock JC.

5. Homodimerization attenuates the anti-inflammatory activity of interleukin-37.
Ellisdon AM, Nold-Petry CA, D'Andrea L, Cho SX, Lao JC, Rudloff I, Ngo D, Lo CY, Soares da Costa TP, Perugini MA, Conroy PJ, Whisstock JC, Nold MF.Sci Immunol. 2017 Feb 10;2(8):eaaj1548. doi: 10.1126/sciimmunol.aaj1548.

Additional publications

A full list of Whistock Lab publications can be viewed on PubMed.