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Truong Group

Polymers and Nanoparticles for Targeted Delivery

The Truong group focuses on developing new polymer chemistry and nanotechnology to address global health challenges such as pandemics, cardiovascular diseases, cancers and antibiotic resistance. We design and synthesise tiny nanosized particles to protect medicines (drugs, nucleic acids, proteins) from in vivo degradation and to prolong their blood circulation time. Importantly, the nanoparticles can carry the medicines to targeted tissues (for example tumours, lymph nodes, spleen, blood clots) and the right cells in our body (for example cancer cells or immune cells). We have successfully prepared a number of new targeted delivery platforms ranging from lipid nanoparticles to smart hybrid polymer nanocarriers for improving the treatment of various diseases. Our group is also dedicated to creating important new knowledge of interactions between nanoparticles and cells under blood flow conditions. We are particularly interested in nanoparticle interactions with immune cells for making better vaccines against viruses, cancers and autoimmune diseases. Furthermore, we aim to exploit polymer chemistry to address other biomedical challenges, such as antibiotic resistance, PEG immunogenicity and nucleic acid stability. We firmly believe that many unmet medical needs can be fulfilled by exploiting nanotechnology and polymer chemistry.


Join us

We welcome enthusiastic, motivated, creative and kindhearted students (Honours, Masters and PhD) as well as Postdocs and visitors who accept our group philosophy to join us. Projects are available across all our research topics, or we can discuss and make one for you. If you don't have a student scholarship or a Postdoc fellowship, we will try our best to help you get one. Please contact Dr Truong for more details:

We are always happy to talk to potential collaborators. If you face a research challenge and think we can help, please send us an email.

We are also delighted to hear from potential donors and gratefully acknowledge the funding given to our group by the Australian Research Council (ARC), the National Health and Medical Research Council (NHMRC), the Honourable Geoffrey Connard and Monash University.


Group philosophy

Global health challenges are complicated and difficult to address by scientists in one research field. As such, we have built an interdisciplinary research group to solve complex health challenges. All our group members are happy to identify emerging challenges, learn the latest techniques, develop new technology, and explore further research avenues. We also need to collaborate and learn from world-leading experts in each field, bringing them together to find solutions for today's challenges. Our goal is to connect experts from different fields, so we all can speak the same language, and understand the challenges, ideas, and solutions.