Chai lab publications

Selected highlight publications

1. Yeatman, H.R., Albiston, A.L., Burns, P. and Chai, S.Y. 2016 Forebrain neuron-specific deletion of insulin-regulated aminopeptidase causes age related deficits in memory.  Neurobiology of Learning and Memory 136:174-182.

2. Diwakarla, S., Nylander, E., Grönbladh, A., Vanga, S.R., Khan, Y.S., Gutiérrez-de-Terán, H., Ng, L., Pham, V., Sävmarker, J., Lundbäck, T., Jenmalm-Jensen, A., Andersson, H., Engen, K., Rosenström, U., Larhed, M., Åqvist, J., Chai, S.Y., and Hallberg, M.  2016 Binding to and inhibition of insulin-regulated aminopeptidase (IRAP) by macrocyclic disulfides enhances spine density.  Molecular Pharmacology 89(4):413-424.

3. Mountford S, Albiston AL, Charman W, Ng L, Holien J, Parker MW, Nicolazzo J, Thompson P and Chai SY. 2014. Synthesis, structure-activity relationships and brain uptake of a novel series of benzopyran inhibitors of insulin-regulated aminopeptidase. Journal of Medicinal Chemistry 57(4):1368-1377.

4. Albiston, A.L., Diwakarla, S., Fernando, R.N., Mountford, S.J., Yeatman, H., Morgan, B., Pham, V., Holien_, J.K.,  Parker, M.W., Thompson, P.E. and  Chai, S.Y. 2011  Identification and development of specific inhibitors for insulin-regulated aminopeptidase as a new class of cognitive enhancers.  British Journal of Pharmacology 164:137-147.

Additional publications

A full list of Chai Lab publications can be viewed on Scopus